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首页> 外文期刊>Medical image analysis >From arteriographies to computational flow in saccular aneurisms: the INRIA experience.
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From arteriographies to computational flow in saccular aneurisms: the INRIA experience.

机译：从动脉造影到囊状动脉瘤的计算流程：INRIA经验。

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Saccular aneurisms illustrate usefulness and possible techniques of image-based modeling of flow in diseased vessels. Aneurism flow is investigated in order to estimate the rupture risk, assuming that the pressure is the major factor and that high-pressure zones are correlated to within-wall strong-stress concentrations. Computational flow is also aimed at providing additional arguments for the treatment strategy. Angiographies of aneurismal vessels of large and medium size are processed to provide three-dimensional reconstruction of the vessel region of interest. Different reconstruction techniques are used for a side and a terminal aneurisms. Reconstruction techniques may lead to different geometries especially with poor input data. The associated facetisation is improved to get a computation-adapted surface triangulation, after a treatment of vessel ends and mesh adaptation. Once the volumic mesh is obtained, the pulsatile flow of an incompressible Newtonian blood is computed using in vivo non-invasive flowmetry and the finite element method. High pressure zones are observed in the aneurism cavity. The pressure magnitude in the aneurism, the location and the size of high pressure zones depend mainly on the aneurism implantation on the vessel wall and its orientation with respect to the blood flux in the upstream vessel. The stronger the blood impacts on the aneurismal wall the higher the pressure. The state of the aneurism neck, where a high-pressure zone can occur, and the location of the aneurism, with an easy access or not, give arguments for the choice between coiling and surgical clipping. Mesh size and 3D reconstruction procedure affect the numerical results. Helpful qualitative data are provided rather than accurate quantitative results in the context of multimodeling.
机译：囊状动脉瘤说明了病变血管中基于图像的血流建模的有用性和可能的​​技术。假设压力是主要因素，而高压区与壁内强应力浓度相关，则研究动脉瘤流量以评估破裂风险。计算流程还旨在为治疗策略提供更多依据。对大中型动脉瘤血管进行血管造影，以对感兴趣的血管区域进行三维重建。不同的重建技术被用于侧面和末端动脉瘤。重建技术可能导致不同的几何形状，尤其是在输入数据较差的情况下。在处理完血管端部并进行网格调整后，相关联的构面得到了改进，从而获得了适用于计算的表面三角剖分。一旦获得了体积网格，就可以使用体内非侵入式流量计和有限元方法来计算不可压缩牛顿血液的搏动流量。在动脉瘤腔中观察到高压区。动脉瘤中的压力大小，高压区的位置和大小主要取决于动脉瘤在血管壁上的植入及其相对于上游血管中血流的方向。血液对动脉瘤壁的影响越大，压力越高。动脉瘤颈部的状态（可能会出现高压区）以及动脉瘤的位置（是否易于进入）为盘绕和手术钳夹之间的选择提供了依据。网格大小和3D重建过程会影响数值结果。在多模型化的情况下，提供了有用的定性数据，而不是准确的定量结果。

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