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首页> 外文期刊>Medical image analysis >Lagrangian frame diffeomorphic image registration: Morphometric comparison of human and chimpanzee cortex.
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Lagrangian frame diffeomorphic image registration: Morphometric comparison of human and chimpanzee cortex.

机译：拉格朗日框架微晶图像配准：人类和黑猩猩皮质的形态比较。

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We develop a novel Lagrangian reference frame diffeomorphic image and landmark registration method. The algorithm uses the fixed Langrangian reference frame to define the map between coordinate systems, but also generates and stores the inverse map from the Eulerian to the Lagrangian frame. Computing both maps allows facile computation of both Eulerian and Langrangian quantities. We apply this algorithm to estimating a putative evolutionary change of coordinates between a population of chimpanzee and human cortices. Inter-species functional homologues fix the map explicitly, where they are known, while image similarities guide the alignment elsewhere. This map allows detailed study of the volumetric change between chimp and human cortex. Instead of basing the inter-species study on a single species atlas, we diffeomorphically connect the mean shape and intensity templates for each group. The human statistics then map diffeomorphically into the space of the chimpanzee cortex providing a comparison between species. The population statistics show a significant doubling of the relative prefrontal lobe size in humans, as compared to chimpanzees.
机译：我们开发了一种新颖的拉格朗日参考系衍射图像和地标配准方法。该算法使用固定的Langrangian参考系来定义坐标系之间的地图，但还会生成并存储从Eulerian到Lagrangian框架的逆图。同时计算两个地图可以轻松计算欧拉和朗朗日量。我们将此算法应用于估计黑猩猩和人类皮质之间的坐标的推定进化变化。种间功能同系物明确地固定了已知的图谱，而图像相似性则指导别处的比对。该图允许详细研究黑猩猩和人类皮质之间的体积变化。我们不是将物种间研究基于单个物种图集，而是将每组的平均形状和强度模板微分地联系起来。然后，人类统计数据将变态映射到黑猩猩皮质的空间中，从而提供了物种之间的比较。人口统计数据显示，与黑猩猩相比，人类相对额叶的相对大小明显增加了一倍。

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