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首页> 外文期刊>Medical image analysis >A deformable digital brain atlas system according to Talairach and Tournoux.
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A deformable digital brain atlas system according to Talairach and Tournoux.

机译：根据Talairach和Tournoux提出的可变形数字脑图集系统。

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摘要

Brain atlases are valuable tools which assist neurosurgeons during the planning of an intervention. Since a printed atlas book has several disadvantages-among them the difficulty to map the information onto a patient's individual anatomy-we have developed a digital version of the well-established stereotaxic brain atlas of Talairach and Tournoux. Our atlas system is mainly dedicated to assist neurosurgical planning, and its benefits are: (i) a three-dimensional (3D) representation of most brain structures contained in the Talairach atlas; (ii) a nonrigid matching capability which warps the standard atlas anatomy to an individual brain magnetic resonance imaging (MRI) dataset in a few minutes and which is able to take deformations due to tumors into account; (iii) the integration of several sources of neuroanatomical knowledge; (iv) an interface to a navigation system which allows utilization of atlas information intraoperatively. In this paper we outline the algorithm we have developed to achieve 3D surface models of the brain structures. Moreover, we describe the nonrigid matching method which consists of two tasks: firstly, point correspondences between the atlas and the patient are established in an automatic fashion, and secondly these displacement vectors are interpolated using a radial basis function approach to form a continuous transformation function. To generate appropriate target structures for the first of these tasks, we implemented a quick segmentation tool which is capable to segment the cortex and ventricles in less than 5 min. An evaluation shows that our nonrigid approach is more precise than the conventional piecewise linear matching, though it should be further improved for the region around the deep grey nuclei. Summarizing, we developed a Win32 program which permits the convenient and fast application of standardized anatomy to individual brains which potentially contain tumors.
机译：脑图谱是在计划干预过程中协助神经外科医师的宝贵工具。由于一本印刷的地图册书有几个缺点-其中包括将信息映射到患者个体解剖学上的困难-我们开发了Talairach和Tournoux完善的立体定向脑图集的数字版本。我们的地图集系统主要致力于协助神经外科手术计划，其好处是：（i）Talairach地图集所包含的大多数大脑结构的三维（3D）表示; （ii）非刚性匹配功能，可在几分钟内将标准地图集解剖结构变形为单个脑磁共振成像（MRI）数据集，并且能够考虑到肿瘤引起的变形; （iii）整合神经解剖学知识的几种来源; （iv）导航系统的界面，该界面允许在术中利用地图集信息。在本文中，我们概述了为实现大脑结构的3D表面模型而开发的算法。此外，我们描述了非刚性匹配方法，该方法包括两个任务：首先，以自动方式建立图谱和患者之间的点对应关系，其次，使用径向基函数方法对这些位移矢量进行插值以形成连续变换函数。为了为这些任务中的第一个生成合适的目标结构，我们实现了一种快速的分割工具，该工具能够在不到5分钟的时间内分割皮层和心室。评估表明，我们的非刚性方法比常规的分段线性匹配更精确，尽管对于深灰色核周围的区域应进一步改进。总而言之，我们开发了Win32程序，该程序允许将标准化解剖结构方便快捷地应用于可能包含肿瘤的单个大脑。

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