Alcohol Drinking Mediates the Association between Polymorphisms of ADH1B and ALDH2 and Hepatitis B-Related Hepatocellular Carcinoma

Liu Jessica; Yang Hwai-I; Lee Mei-Hsuan; Jen Chin-Lan; Hu Hui-Han; Lu Sheng-Nan; Wang Li-Yu; You San-Lin; Huang Yen-Tsung; Chen Chien-Jen

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Alcohol Drinking Mediates the Association between Polymorphisms of ADH1B and ALDH2 and Hepatitis B-Related Hepatocellular Carcinoma

机译：饮酒介导ADH1B和ALDH2多态性与乙型肝炎相关的肝细胞癌之间的关联。

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Background: The role of polymorphisms on ADH1B and ALDH2 in patients with chronic hepatitis B is unclear. This study aims to examine whether alcohol drinking mediates the association between two ADH1B and ALDH2 polymorphisms and the risk of hepatocellular carcinoma among chronic hepatitis B patients.

机译：背景：慢性乙型肝炎患者中ADH1B和ALDH2基因多态性的作用尚不清楚。这项研究旨在检查饮酒是否介导了慢性乙型肝炎患者中两个ADH1B和ALDH2多态性之间的关联以及肝细胞癌的风险。

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《Cancer epidemiology, biomarkers and prevention: A publication of the American Association for Cancer Research》 |2016年第4期|共7页
作者
Liu Jessica; Yang Hwai-I; Lee Mei-Hsuan; Jen Chin-Lan; Hu Hui-Han; Lu Sheng-Nan; Wang Li-Yu; You San-Lin; Huang Yen-Tsung; Chen Chien-Jen;
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正文语种 eng
中图分类肿瘤学;
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1. Alcohol Drinking Mediates the Association between Polymorphisms of ADH1B and ALDH2 and Hepatitis B-Related Hepatocellular Carcinoma [J] . Liu Jessica, Yang Hwai-I, Lee Mei-Hsuan, Cancer epidemiology, biomarkers and prevention: A publication of the American Association for Cancer Research . 2016,第4期

机译：饮酒介导ADH1B和ALDH2多态性与乙型肝炎相关的肝细胞癌之间的关联。
2. Aldehyde dehydrogenase 2 (ALDH2) and alcohol dehydrogenase 1B (ADH1B) polymorphisms exacerbate bladder cancer risk associated with alcohol drinking: gene-environment interaction [J] . Masaoka Hiroyuki, Ito Hidemi, Soga Norihito, Carcinogenesis . 2016,第6期

机译：乙醛脱氢酶2（ALDH2）和酒精脱氢酶1B（ADH1B）多态性加剧了与饮酒有关的膀胱癌风险：基因与环境的相互作用
3. Effects of alcohol-drinking behaviour and ADH1B and ALDH2 polymorphisms on basal DNA damage in human mononuclear cells as determined by the comet assay. [J] . Weng H, Weng Z, Lu Y, Mutation Research: International Journal on Mutagenesis, Chromosome Breakage and Related Subjects . 2010,第2期

机译：彗星试验确定了饮酒行为以及ADH1B和ALDH2多态性对人单核细胞基础DNA损伤的影响。
4. Estrogen Receptor Alpha Polymorphisms Associated with Susceptibility to Hepatocellular Carcinoma in Hepatitis B Virus Carriers [C] . YUN ZHAI, HONGXIN ZHANG, LIANTENG ZHI, 中国遗传学会七届二次青年研讨会论文汇编 . 2006

机译：乙型肝炎病毒携带者与肝细胞癌易感性相关的雌激素受体α多态性
5. Progress Towards the Development of a Hepatitis B-dependent Hepatocellular Carcinoma Model System using a Chimeric Human/Mouse Liver Assay. [D] . Cruz, Nathalia. 2014

机译：利用嵌合人/小鼠肝试验开发乙肝依赖型肝细胞癌模型系统的进展。
6. Modification of the Associations of Alcohol Intake With Serum Low-Density Lipoprotein Cholesterol and Triglycerides by ALDH2 and ADH1B Polymorphisms in Japanese Men [O] . Tae Sasakabe, Kenji Wakai, Sayo Kawai, 2018

机译：酒精摄入与血清低密度脂蛋白胆固醇和甘油三酯的关联的ALDH2和ADH1B多态性在日本男性中的应用
7. Alcohol Drinking Mediates the Association between Polymorphisms of ADH1B and ALDH2 and Hepatitis B–Related Hepatocellular Carcinoma [O] . Jessica Liu, Hwai-I Yang, Mei-Hsuan Lee, 2016

机译：酒精饮用介导ADH1B和ALDH2和乙型肝炎相关肝细胞癌多态性之间的关联

Alcohol Drinking Mediates the Association between Polymorphisms of ADH1B and ALDH2 and Hepatitis B-Related Hepatocellular Carcinoma

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