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首页> 外文期刊>Medical and Pediatric Oncology: The Official Journal of the American Association for Cancer Education >Role of surgery in children with rhabdomyosarcoma.
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Role of surgery in children with rhabdomyosarcoma.

机译：手术在小儿横纹肌肉瘤中的作用。

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BACKGROUND: Rhabdomyosarcoma (RMS) is a common soft tissue sarcoma of childhood. Historically, surgery has played a central role in the management of children with this tumor, though with surgery alone survival rates were poor. With current multimodal (surgery, radiotherapy and chemotherapy) treatment of these patients, survival has dramatically improved and, with this improvement, there has been an evolution of the role of surgery in the management of this condition. MATERIAL AND METHOD: The contemporary published literature (English) regarding surgical aspects of pediatric rhabdomyosarcoma was reviewed and evaluated. RESULTS: Multimodal therapy has improved the survival of children with RMS from 25% in 1970 to greater than 70% today. Surgical procedures for childhood RMS today are less apt to be exenterative or mutilating than those employed thirty years ago. CONCLUSIONS: Surgery plays a vital role in the diagnosis and treatment of children with RMS. This role has evolved in the context of multimodaltherapy and improved survival to an emphasis on less radical procedures with decreased morbidity.
机译：背景：横纹肌肉瘤（RMS）是儿童期常见的软组织肉瘤。从历史上看，外科手术在患这种肿瘤的儿童的治疗中起着核心作用，尽管仅手术一项的存活率就很低。通过目前对这些患者的多式联运（手术，放疗和化疗）治疗，生存率得到了显着改善，并且随着这种改善，外科手术在控制这种疾病方面的作用也得到了发展。材料与方法：回顾和评估了有关小儿横纹肌肉瘤手术方面的当代文献（英语）。结果：多模式疗法已将RMS儿童的存活率从1970年的25％提高到今天的70％以上。与三十年前所采用的方法相比，如今用于儿童RMS的外科手术方法更不容易发脾气或残废。结论：手术在RMS儿童的诊断和治疗中起着至关重要的作用。在多模式疗法的背景下，这一作用已经得到了发展，并提高了生存率，重点是减少了发病率，减少了手术的难度。

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