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首页> 外文期刊>Canadian journal of public health: Revue canadienne de sante publique >The relationship between diabetes and tuberculosis in Saskatchewan: comparison of registered Indians and other Saskatchewan people.
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The relationship between diabetes and tuberculosis in Saskatchewan: comparison of registered Indians and other Saskatchewan people.

机译:萨斯喀彻温省糖尿病与结核病的关系:印第安人和其他萨斯喀彻温人的比较。

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摘要

BACKGROUND: Saskatchewan Aboriginal people are experiencing epidemics of both type 2 diabetes (T2DM) and tuberculosis (TB). The purpose of this study was to determine if a relationship exists between diabetes and TB in Saskatchewan and to establish whether there is a difference in the degree of any association between Aboriginal and non-Aboriginal people. METHODS: Utilizing Saskatchewan Health databases, TB incidence (cases identified from 1986-2001) was compared between four subpopulations identified from 1991-1995: Registered Indians (RI) with and without diabetes, and other Saskatchewan people (OSKP) with and without diabetes. RESULTS: Diabetic women aged 20-59 years had higher average annual incidence rates of TB than non-diabetic women, but within-population rate ratios of TB in diabetic versus non-diabetic women were only significant in those aged 50-59 (2.7 [CI 1.28, 5.72] in RI and 3.9 [CI 1.58, 9.67] in OSKP). No other within-population diabetic subgroup had significantly higher rates of TB. The only male diabetic group that had a higher rate of TB were RI plus OSKP men aged 50-59 years. Overall, diabetes preceded TB in 87/111 individuals with both diseases (p < 0.0001). CONCLUSIONS: Our results suggest that T2DM is a predictor for TB in Saskatchewan women aged 20-59 but particularly in RI and OSKP women aged 50-59 years. This has implications for TB screening and prevention initiatives.
机译:背景:萨斯喀彻温省土著人民正经历着2型糖尿病(T2DM)和结核病(TB)的流行。这项研究的目的是确定萨斯喀彻温省的糖尿病与结核病之间是否存在关系,并确定原住民与非原住民之间任何关联的程度是否存在差异。方法:利用萨斯喀彻温省健康数据库,比较1991年至1995年确定的四个亚人群的结核病发病率(1986年至2001年确定的病例):患有和不患有糖尿病的注册印第安人(RI),以及患有或不患有糖尿病的其他萨斯喀彻温人(OSKP)。结果:20-59岁的糖尿病妇女的结核病年平均发病率高于非糖尿病妇女,但糖尿病和非糖尿病妇女的结核病人口内比率仅在50-59岁的妇女中显着(2.7 [ RI中的CI为1.28、5.72],OSKP中的CI为[CI 1.58、9.67]。没有其他人群内糖尿病亚组的结核病发病率显着更高。唯一具有较高结核病率的男性糖尿病人群是50岁至59岁的RI加OSKP男性。总体而言,在两种疾病的87/111个人中,糖尿病先于结核病(p <0.0001)。结论:我们的结果表明,T2DM是萨斯喀彻温省20-59岁女性中TB的预测因子,但特别是50-59岁的RI和OSKP女性中TB的预测。这对结核病筛查和预防计划具有影响。

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