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首页> 外文期刊>Medical Physics >A comparison of the respiratory signals acquired by different respiratory monitoring systems used in respiratory gated radiotherapy.
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A comparison of the respiratory signals acquired by different respiratory monitoring systems used in respiratory gated radiotherapy.

机译：由门控放疗中使用的不同呼吸监测系统获取的呼吸信号的比较。

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PURPOSE: Respiratory monitoring systems are used to detect the respiratory phase of patients during the planning and administration of respiratory gated radiotherapy by using four-dimensional computed tomography (4DCT) or 4D positron-emission tomography/CT (4DPET/CT) and the linear accelerator (linac), respectively. Generally, identical respiratory monitoring systems are used for 4DCT, 4DPET/CT, and linac. However, different systems are sometimes used in combination because the accessibility of the respiratory monitoring systems may differ by manufacturer. The combined use of different respiratory monitoring systems in phase-based gating is of concern because the differences in the timing of tags (end-respiration signals algorithmically determined by the respiratory monitoring system), defined by the two systems, may result in phase differences, The purpose of this study is to estimate this difference and evaluate its effect on 4DCT data. METHODS: Ten patients (seven men and three women) with a median age of 75 yr (range: 57-84 yr) were treated by gated stereotactic body radiation therapy between April and December 2009. Two types of respiratory monitoring systems--RPM (Varian Medical Systems) and AZ-733V (Anzai MEDICAL)--were placed on the abdominal surface of the patients, and the respiratory signals were acquired by both systems. The relationship between the amplitude peak and the tag obtained by each respiratory system was analyzed for each patient. Further, the 4DCT images were reconstructed by using the signals obtained from both the RPM and the AZ-733V systems, and the tumor volumes and the tumor centroid positions in the craniocaudal plane were analyzed for each patient. RESULTS: The correlation factor between the respiratory signals from the RPM system and AZ-733V system was 0.990 (range: 0.940-0.994). The amplitude peak of the RPM system corresponded well with that of the AZ-733V system. The median +/- standard deviation of the phase difference for all the patients ranged from -4.3 +/- 7.1% to 3.5 +/- 2.2%. In the case of some patients, differences were noted between the two systems in the estimation of the tumor centroid position and tumor shape. CONCLUSIONS: The estimation of the position of the tumor centroid and tumor shape may vary with the use of different respiratory monitoring systems. This implies that it is preferable to use the same respiratory monitoring system with 4DCT, 4DPET-CT, and linac.
机译：目的：通过使用二维计算机断层扫描（4DCT）或4D正电子发射断层扫描/ CT（4DPET / CT）和线性加速器，在呼吸门控放疗的计划和管理过程中使用呼吸监测系统来检测患者的呼吸阶段（直线加速器）。通常，相同的呼吸监控系统用于4DCT，4DPET / CT和直线加速器。但是，有时会组合使用不同的系统，因为呼吸监控系统的可访问性可能因制造商而异。不同呼吸监控系统在基于相位的门控中的组合使用值得关注，因为两个系统定义的标签时序（由呼吸监控系统算法确定的最终呼吸信号）的时间差异可能会导致相位差异，这项研究的目的是估计这种差异并评估其对4DCT数据的影响。方法：2009年4月至2009年12月间，采用门控立体定向放射疗法治疗了10名中位年龄为75岁（范围：57-84岁）的患者（七名男性和三名女性）。两种呼吸监测系统-RPM（瓦里安医疗系统（Varian Medical Systems）和AZ-733V（安扎医疗（Anzai MEDICAL））放置在患者的腹部表面上，两个系统都采集了呼吸信号。对每个患者分析振幅峰值和每个呼吸系统获得的标签之间的关系。此外，通过使用从RPM和AZ-733V系统获得的信号重建4DCT图像，并对每个患者的颅尾平面中的肿瘤体积和肿瘤质心位置进行分析。结果：RPM系统和AZ-733V系统的呼吸信号之间的相关系数为0.990（范围：0.940-0.994）。 RPM系统的振幅峰值与AZ-733V系统的振幅峰值非常吻合。所有患者的相位差的中值+/-标准偏差范围为-4.3 +/- 7.1％至3.5 +/- 2.2％。在某些患者的情况下，两个系统在估计肿瘤质心位置和肿瘤形状方面存在差异。结论：肿瘤质心的位置和肿瘤形状的估计可能因使用不同的呼吸监测系统而异。这意味着最好将同一呼吸监测系统与4DCT，4DPET-CT和直线加速器一起使用。

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