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An in-shoe laser Doppler sensor for assessing plantar blood flow in the diabetic foot.

机译:鞋内激光多普勒传感器,用于评估糖尿病足的足底血流。

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摘要

Increased pressure due, to sensory neuropathy, is important in the development of plantar ulceration in type II diabetes. However, additional factors are thought to pre-dispose the skin tissue to ulceration. Autonomic neuropathy and microangiopathy are the basis for the capillary steal theory and the haemodynamic hypothesis, developed to explain the aetiology of this type of ulcer, in terms of microvascular complications. The aim of the present study was to develop a system to allow assessment of blood flow at prevalent sites of ulceration. Previous studies have been limited to assessment of the bare foot under rest conditions. The new system allows measurements to be made in-shoe, during static and dynamic loading. The system comprises a laser Doppler sensor, a load sensor, measurement shoe, instrumentation and analysis software. The measurement shoe was designed to minimise movement artefact and provide thermal insulation for the foot. A simple flow rig was used to characterise the sensor. The blood flux response was linear (q5% deviation from ideal) for particle concentrations up to 0.25% and for mean particle velocities up to 8mms(-1). The worst case drift in the response over a six-month period was 3.7%. Device to device repeatability varied by 12.5% over five devices.
机译:感觉神经病引起的压力升高对II型糖尿病足底溃疡的发展很重要。然而,认为其他因素会使皮肤组织易于溃疡。自主神经病变和微血管病是毛细血管盗窃理论和血液动力学假说的基础,该假说旨在通过微血管并发症来解释此类溃疡的病因。本研究的目的是开发一种系统,以评估溃疡流行部位的血流量。先前的研究仅限于在休息条件下评估赤脚。新系统允许在静态和动态加载过程中在鞋内进行测量。该系统包括一个激光多普勒传感器,一个负载传感器,一个测量靴,仪器和分析软件。测量鞋的设计旨在最大程度地减少运动伪影并为脚提供热绝缘。使用简单的流动装置来表征传感器。对于高达0.25%的颗粒浓度和高达8mms(-1)的平均颗粒速度,血流响应是线性的(偏离理想值q5%)。在六个月内,响应中最差的情况漂移为3.7%。在五个设备上,设备到设备的重复性变化了12.5%。

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