...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Medical engineering & physics. >Inter-scanner differences in in vivo QCT measurements of the density and strength of the proximal femur remain after correction with anthropomorphic standardization phantoms
【24h】

Inter-scanner differences in in vivo QCT measurements of the density and strength of the proximal femur remain after correction with anthropomorphic standardization phantoms

机译：用拟人化标准化体模校正后，体内QCT测量的股骨近端密度和强度在扫描仪间存在差异

获取原文
获取原文并翻译 | 示例
   

获取外文期刊封面封底 >>

       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

In multicenter studies and longitudinal studies that use two or more different quantitative computed tomography (QCT) imaging systems, anthropomorphic standardization phantoms (ASPs) are used to correct inter-scanner differences and allow pooling of data. In this study, in vivo imaging of 20 women on two imaging systems was used to evaluate inter-scanner differences in hip integral BMD (iBMD), trabecular BMD (tBMD), cortical BMD (cBMD), femoral neck yield moment (My) and yield force (Fy), and finite-element derived strength of the femur under stance (FEstance) and fall (FEfall) loading. Six different ASPs were used to derive inter-scanner correction equations. Significant (p0.05) inter-scanner differences were detected in all measurements except My and FEfall, and no ASP-based correction was able to reduce inter-scanner variability to corresponding levels of intra-scanner precision. Inter-scanner variability was considerably higher than intra-scanner precision, even in cases where the mean inter-scanner difference was statistically insignificant. A significant (p0.01) effect of body size on inter-scanner differences in BMD was detected, demonstrating a need to address the effects of body size on QCT measurements. The results of this study show that significant inter-scanner differences in QCT-based measurements of BMD and bone strength can remain even when using an ASP.
机译：在使用两个或多个不同的定量计算机断层扫描（QCT）成像系统的多中心研究和纵向研究中，拟人化标准化体模（ASP）用于纠正扫描器间的差异并允许合并数据。在这项研究中，使用两个成像系统对20名女性进行了体内成像，以评估扫描仪之间的髋部积分BMD（iBMD），小梁BMD（tBMD），皮质BMD（cBMD），股骨屈服力矩（My）和屈服力（Fy），以及在姿态（FEstance）和跌落（FEfall）载荷下股骨的有限元派生强度。使用六个不同的ASP导出扫描仪间校正方程。除My和FEfall外，所有测量均检测到显着的（p <0.05）扫描仪间差异，并且没有基于ASP的校正能够将扫描仪间的可变性降低到相应的扫描仪内精度水平。即使在平均扫描仪间差异在统计学上不显着的情况下，扫描仪间的差异性也明显高于扫描仪内的精度。检测到人体大小对BMD扫描仪间差异的显着（p <0.01）影响，表明需要解决人体大小对QCT测量的影响。这项研究的结果表明，即使使用ASP，在基于QCT的BMD和骨强度测量中，扫描器之间仍存在显着差异。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号