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Recognition and Impact of Host-derived Molecules on Bacterial Cell-to-cell Signalling Pathways

机译:宿主分子对细菌细胞间信号通路的识别和影响

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摘要

Microbe-host signalling is now a well accepted concept and an intensively studied research field. Although some of the observed bacterial phenotypes are atributed to host-recognition and inter-kingdom signalling, most of them are not relying on a proved molecular mechanism. Recent progress revealed some recognition and signalling pathways for host molecules in bacterial cells, which try to explain their modulatory effect on growth and virulence. Since the current knowledge on the field is poor and debatable, the purpose of this paper is to review and discuss the research performed in order to elucidate the ways by which microbial cells recognize and decode the host molecule signals.
机译:微生物宿主信号传导现在是一个广为接受的概念,也是一个深入研究的研究领域。尽管观察到的某些细菌表型归因于宿主识别和王国间信号传导,但它们中的大多数并不依赖于已证明的分子机制。最近的进展揭示了细菌细胞中宿主分子的一些识别和信号传导途径,试图解释它们对生长和毒力的调节作用。由于目前在该领域的知识贫乏且值得商bat,因此本文的目的是回顾和讨论所进行的研究,以阐明微生物细胞识别和解码宿主分子信号的方式。

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