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首页> 外文期刊>Medicine. >The efficacy and safety of panitumumab plus irrinotecan-based chemotherapy in the treatment of metastatic colorectal cancer A meta-analysis
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The efficacy and safety of panitumumab plus irrinotecan-based chemotherapy in the treatment of metastatic colorectal cancer A meta-analysis

机译:帕尼单抗联合以伊立替康为基础的化学疗法治疗转移性结直肠癌的疗效和安全性荟萃分析

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摘要

Background: Panitumumab, a fully human monoclonal antibody targeting epidermal growth factor receptor, is used in combination with chemotherapy for patients with metastatic colorectal cancer (mCRC). However, the effects of panitumumab in combination with irrinotecan-based chemotherapy remain uncertain. Therefore, we conducted this meta-analysis to assess the efficacy and safety of combination treatment of panitumumab plus chemotherapy in the treatment of mCRC.
机译:背景:Panitumumab是靶向表皮生长因子受体的完全人类单克隆抗体,与转移性结直肠癌(mCRC)患者联合使用。然而,帕尼单抗联合以伊立替康为基础的化学疗法的效果仍不确定。因此,我们进行了这项荟萃分析,以评估帕尼单抗联合化疗联合化疗治疗mCRC的疗效和安全性。

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