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首页> 外文期刊>Medycyna Weterynaryjna >Range of susceptibility of Paenibacillus larvae to antibacterial compoundsOriginal Title (non-English) Spektrum wrazliwosci Paenibacillus larvae na dzialanie zwiazkow antybakteryjnych [Polish]
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Range of susceptibility of Paenibacillus larvae to antibacterial compoundsOriginal Title (non-English) Spektrum wrazliwosci Paenibacillus larvae na dzialanie zwiazkow antybakteryjnych [Polish]

机译：杆状芽孢杆菌幼虫对抗菌化合物的敏感性范围原始名称（非英语）杆状芽孢杆菌幼虫对抗菌化合物的敏感性谱[波兰语]

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摘要

The honey bee disease American foulbrood (AFB) is a serious problem since its causative agent (Paenibacillus larvae) has become increasingly resistant to conventional antibiotics. From the year 2000 the number of isolates of P. larvae resistant against oxytetracycline (OTC) has increased. Therefore, since 2000 many antibiotics, chemotherapeutic propolis and plant extracts were tested in vitro and in vivo against P. larvae. The most active in the in vitro tests appeared to be deoxycycline, minocycline, rifampicin and lincomycin. Among the 35 examined antibacterial compounds active against P. larvae were narasin, salinomycin and tylosine. In many countries tylosine, tilomycosis have been recommended for the control of AFB, while microsamicine was recommended in Japan. The studies with plain essential oils did not succeeded. The propolis extracts from the various parts of the world showed significant inhibition of P. larvae. Due to the evolution of the resistance of P. larvae to conventional antibiotic treatments, the research on normal bee microflora (Bacillus, Paenibacillus, and Brevibacillus) is an important step in identifying possible new active tools to treat AFB in honey bee colonies.
机译：蜜蜂疾病美洲臭蝇（AFB）是一个严重的问题，因为其病原体（Paenibacillus larvae）对常规抗生素的耐药性越来越高。从2000年开始，抗土霉素的幼虫分离株数量增加。因此，自2000年以来，在体外和体内测试了许多抗疟原虫幼虫的抗生素，化学蜂胶和植物提取物。在体外测试中最活跃的似乎是脱氧环素，米诺环素，利福平和林可霉素。在检查的对幼虫有活性的35种抗菌化合物中，有萘乐菌素，沙利霉素和酪氨酸。在许多国家，已建议使用酪氨酸，真菌病来控制AFB，而在日本则建议使用微土霉素。用普通香精油的研究没有成功。来自世界各地的蜂胶提取物显示出对小菜蛾幼虫的显着抑制作用。由于P.幼虫对常规抗生素治疗的抗性演变，对正常蜜蜂微生物区系（芽孢杆菌，芽孢杆菌和短杆菌）的研究是确定可能的新方法来治疗蜜蜂群体中AFB的重要步骤。

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