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A population-based, case-control study of green tea consumption and leukemia risk in southwestern Taiwan.

机译:一项基于人口的台湾西南部绿茶消费和白血病风险病例对照研究。

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OBJECTIVE: This study investigated the association between green tea consumption and leukemia. METHODS: A total of 252 cases (90.3% response) and 637 controls (53.4% response) were enrolled. Controls were matched for cases on age and gender. Information was collected on participants' living habits, including tea consumption. Green tea was used as a standard to estimate the total amount of individual catechin consumption. We stratified individual consumption of catechins into four levels. Conditional logistic regression models were fit to subjects aged 0-15 and 16-29 years to evaluate separate associations between leukemia and catechin consumption. RESULTS: A significant inverse association between green tea consumption and leukemia risk was found in individuals aged 16-29 years, whereas no significant association was found in the younger age groups. For the older group with higher amounts of tea consumption (>550 units of catechins), the adjusted odds ratio (OR) compared with the group without tea consumption was 0.47 [95% confidence interval (CI) = 0.23-0.97]. After we adjusted for smoking status and medical irradiation exposure, the overall OR for all participants was 0.49 (95% CI = 0.27-0.91), indicating an inverse relation between large amounts of catechins and leukemia. CONCLUSION: Drinking sufficient amounts of tea, especially green tea, which contains more catechins than oolong tea and black tea, may reduce the risk of leukemia.
机译:目的:本研究调查了绿茶消费与白血病之间的关系。方法:共纳入252例(90.3%缓解)和637例对照(53.4%缓解)。对照是针对年龄和性别的病例。收集了有关参与者的生活习惯的信息,包括饮茶。绿茶被用作估计个体儿茶素消费总量的标准。我们将儿茶素的个人消费分为四个级别。有条件的逻辑回归模型适用于0-15岁和16-29岁的受试者,以评估白血病和儿茶素消费之间的独立关联。结果:在16-29岁的人群中发现绿茶消费与白血病风险之间存在显着的负相关关系,而在较年轻的年龄组中则没有显着的相关关系。对于茶消费量较大(> 550单位儿茶素)的老年组,与未喝茶的组相比,调整后的优势比(OR)为0.47 [95%置信区间(CI)= 0.23-0.97]。在调整了吸烟状况和医疗照射暴露后,所有参与者的总OR均为0.49(95%CI = 0.27-0.91),表明大量儿茶素和白血病之间存在反比关系。结论:喝足够量的茶,尤其是绿茶,其儿茶素含量比乌龙茶和红茶高,可以降低患白血病的风险。

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