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Correlates of sexually transmitted infection histories in a cohort of American male health professionals.

机译:美国男性卫生专业人员队伍中性传播感染史的相关性。

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OBJECTIVE: Several epidemiologic studies have investigated sexually transmitted infections (STIs) and later risk of genitourinary conditions with suggestive positive results. While these results may reflect causal associations, other possible explanations include confounding by factors possibly related to both STI acquisition and genitourinary condition risk such as recognized STI-risk factors/correlates, and other factors not typically considered in relation to STIs (e.g., general health-related behaviors or markers of such behaviors). Very few of these factors have been investigated in older populations in which STIs and genitourinary conditions are typically studied. Therefore, we investigated STI history correlates in one such population, the Health Professionals Follow-up Study. METHODS: We ascertained histories of potential correlates, gonorrhea, syphilis by questionnaire (n = 36,032), and performed serologic testing for Chlamydia trachomatis, Trichomonas vaginalis, human papillomavirus, and human herpesvirus type 8 infection in a subset (n = 651). RESULTS: Positive correlations were observed for African-American race, foreign birth, southern residence, smoking, alcohol consumption, ejaculation frequency, vasectomy, and high cholesterol. Inverse correlations were observed for social integration and routine health-related examinations. CONCLUSIONS: These findings provide useful information on potential confounders for epidemiologic investigations of STIs and chronic diseases, and interesting new hypotheses for STI prevention (e.g., STI counseling before vasectomy).
机译:目的:几项流行病学研究调查了性传播感染(STIs)和以后发生泌尿生殖系统疾病的风险,并提示阳性结果。尽管这些结果可能反映了因果关系,但其他可能的解释包括与可能与性传播感染获取和泌尿生殖道疾病风险相关的因素所混淆,例如公认的性传播感染风险因素/相关性,以及通常不考虑与性传播感染相关的其他因素(例如,一般健康状况)相关行为或此类行为的标记)。在通常研究性传播感染和泌尿生殖系统疾病的老年人口中,对这些因素的研究很少。因此,我们调查了此类人群中的STI历史相关性,即Health Professionals跟进研究。方法:我们通过问卷调查(n = 36,032)确定了潜在相关性,淋病,梅毒的病史,并在亚组中对沙眼衣原体,阴道毛滴虫,人乳头瘤病毒和人8型疱疹病毒感染进行了血清学检测(n = 651)。结果:观察到与非裔美国人种族,外国出生,南部居住,吸烟,饮酒,射精频率,输精管结扎术和高胆固醇相关。在社会融合和常规健康相关检查中观察到反相关。结论:这些发现为性传播感染和慢性病的流行病学调查提供了有用的信息,包括潜在的混杂因素,以及有关性传播感染预防的有趣新假设(例如,输精管切除术之前的性传播疾病咨询)。

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