首页> 外文期刊>Metabolic syndrome and related disorders >Prevalence and correlates of diabetes in South asian indians in the United States: findings from the metabolic syndrome and atherosclerosis in South asians living in america study and the multi-ethnic study of atherosclerosis.
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Prevalence and correlates of diabetes in South asian indians in the United States: findings from the metabolic syndrome and atherosclerosis in South asians living in america study and the multi-ethnic study of atherosclerosis.

机译:美国南亚印第安人的糖尿病患病率和相关性:居住在美国的南亚人的代谢综合征和动脉粥样硬化研究结果以及动脉粥样硬化的多种族研究。

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BACKGROUND: Individuals from South Asia have high diabetes prevalence despite low body weight. We compared the prevalence of diabetes among South Asian Indians with other U.S. ethnic groups and explored correlates of diabetes. METHODS: This was a cross-sectional study of 150 South Asian Indians (ages 45-79) in California, using similar methods to the Multi-Ethnic Study of Atherosclerosis (MESA). Type 2 diabetes was classified by fasting plasma glucose (FPG) >or=126 mg/dL, 2-h postchallenge glucose >or=200 mg/dL, or use of hypoglycemic medication. RESULTS: A total of 29% of Asian Indians had diabetes, 37% had prediabetes, and 34% had normal glucose tolerance. After full adjustment for covariates, Indians still had significantly higher odds of diabetes compared to whites and Latinos, but not significantly different from African Americans and Chinese Americans in MESA: Indians [odds ratio (OR), 1.0], whites [OR, 0.29; 95% confidence interval (CI), 0.17-0.49], Latinos (OR, 0.59; CI, 0.34-1.00) African Americans (OR, 0.77; CI 0.45-1.32), Chinese Americans (OR, 0.78, CI, 0.45-1.32). Variables associated with prediabetes or diabetes among Indians included hypertension, fatty liver, visceral adiposity, microalbuminuria, carotid intima media thickness, and stronger traditional Indian beliefs. CONCLUSIONS: Indian immigrants may be more likely to have diabetes than other U.S. ethnic groups, and cultural factors may play a role, suggesting that this is a promising area of research.
机译:背景:尽管体重较轻,但来自南亚的个体仍具有较高的糖尿病患病率。我们将南亚印第安人与其他美国种族中的糖尿病患病率进行了比较,并探讨了糖尿病的相关性。方法:这是一项对150名在加利福尼亚州的南印度人(45-79岁)进行的横断面研究,使用的方法与多民族动脉粥样硬化研究(MESA)相似。 2型糖尿病通过空腹血糖(FPG)≥126mg / dL,激发后2小时葡萄糖≥or200 mg / dL或使用降糖药进行分类。结果:总共29%的亚洲印度人患有糖尿病,37%的糖尿病前期患者和34%的糖耐量正常。在对协变量进行全面调整后,印度人的糖尿病几率仍高于白人和拉丁裔,但在MESA方面与非裔美国人和华裔美国人没有显着差异:印地安人[赔率(OR),1.0],白人[OR,0.29; 95%置信区间(CI),0.17-0.49],拉丁美洲人(OR,0.59; CI,0.34-1.00)非洲裔美国人(OR,0.77; CI 0.45-1.32),华裔美国人(OR,0.78,CI,0.45-1.32 )。印度人中与糖尿病前期或糖尿病相关的变量包括高血压,脂肪肝,内脏脂肪,微量蛋白尿,颈动脉内膜中层厚度以及印度传统观念的增强。结论:与美国其他种族相比,印度移民更可能患有糖尿病,并且文化因素也可能起作用,这表明这是一个有前途的研究领域。

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