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CYLD and HCC: When Being Too Sensitive to Your Dirty Neighbors Results in Self-Destruction

机译:CYLD和HCC:对肮脏的邻居过于敏感会导致自我毁灭

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摘要

Hepatocellular carcinoma is the outcome of ongoing cycles of cell death and regeneration in chronic liver disease. In this issue of Cancer Cell, Nikolaou et al. show that the deubiquitinating enzyme CYLD is critical for controlling the balance between hepatocyte loss, regeneration, and malignant progression.
机译:肝细胞癌是慢性肝病中持续的细胞死亡和再生周期的结果。在本期《癌细胞》中,Nikolaou等人。结果表明,去泛素化酶CYLD对于控制肝细胞丢失,再生和恶性进展之间的平衡至关重要。

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