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Decreased serum zinc is an effect of ageing and not Alzheimer's disease

机译:血清锌减少是衰老的影响,而不是阿尔茨海默氏病

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We examined the distribution of zinc in the periphery (erythrocytes and serum) in a large, well-characterised cohort, the Australian Imaging, Biomarkers and Lifestyle (AIBL) study, in order to determine if there is systemic perturbation in zinc homeostasis in Alzheimer's disease (AD). We observed an age dependent decrease in serum zinc of approximately 0.4% per year. When correcting for the age dependent decline in serum zinc no significant difference between healthy controls (HC), mildly cognitively impaired (MCI) or AD subjects was observed
机译:为了确定阿尔茨海默氏病患者体内锌稳态中是否存在系统性扰动,我们在澳大利亚影像,生物标志物和生活方式研究(AIBL)的一项大型队列研究中,研究了锌在外周(红细胞和血清)中的分布情况。 (广告)。我们观察到年龄相关的血清锌每年减少约0.4%。校正年龄依赖性的血清锌下降后,健康对照(HC),轻度认知障碍(MCI)或AD受试者之间无显着差异

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