A Review on the Development in the Field of NIDDM based Thiazolidinedione PPARγ Agonists.

Pooja S Banerjee; Subir Samanta

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A Review on the Development in the Field of NIDDM based Thiazolidinedione PPARγ Agonists.

机译：基于NIDDM的噻唑烷二酮PPARγ激动剂的研究进展。

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Peroxisome Proliferator Activated Receptors gamma (PPARγ) are a class of ligand activated transcriptionfactors with a prominent role in the regulation of metabolic processes. The present work aims towards examining thefunctional and structural features that facilitate the binding of small molecules based on Thiazolidinedione pharmacophoreto PPARs. The intent of this article is to review all the reported thiazolidinediones and associated groups of PPARγligands.

机译：过氧化物酶体增殖物激活受体γ（PPARγ）是一类配体激活的转录因子，在代谢过程的调节中起重要作用。本工作旨在研究促进基于噻唑烷二酮药效团与PPAR的小分子结合的功能和结构特征。本文的目的是审查所有已报道的噻唑烷二酮和相关的PPARγ配体基团。

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《Mini reviews in medicinal chemistry》 |2013年第5期|共7页
作者
Pooja S Banerjee; Subir Samanta;
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A Review on the Development in the Field of NIDDM based Thiazolidinedione PPARγ Agonists.

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