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Investigation and management of non-immune fetal hydrops

机译：非免疫性胎儿积水的调查和处理

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Objective: To describe the current investigation and management of non-immune fetal hydrops, with a focus on treatable or recurring etiologies. Outcomes: To provide better counselling and management in cases of prenatally diagnosed non-immune hydrops.Evidence: Published literature was retrieved through searches of PubMed or MEDLINE, CINAHL, and The Cochrane Library in 2011 using key words (non-immune hydrops fetalis, fetal hydrops, fetal therapy, fetal metabolism). Results were restricted to systematic reviews, randomized controlled trials/controlled clinical trials, observational studies, and significant case reports. Additional publications were identified from the bibliographies of these articles. There were no date or language restrictions. Searches were updated on a regular basis and incorporated in the guideline to May 2012. Grey (unpublished) literature was identified through searching the websites of health technology assessment and health technology-related agencies, clinicaJ practice guideline collections, clinical trial registries, and national and international medical specialty societies.Benefits, harms, and costs: These guidelines educate readers about the causes of non-immune fetal hydrops and its prenatal counselling and management. It also provides a standardized approach to non-immune fetal hydrops, emphasizing the search for prenatally treatable conditions and recurrent genetic etiologies.Values: The quality of evidence in this document was rated using the criteria described in the Report of the Canadian Task Force on Preventive Health Care (Table 1).
机译：目的：描述目前非免疫性胎儿积水的调查和管理，重点是可治疗或复发的病因。结果：为产前诊断的非免疫性积水提供更好的咨询和管理。证据：2011年通过使用关键词（非免疫性积水，胎儿，胎儿）检索PubMed或MEDLINE，CINAHL和Cochrane图书馆检索了已发表的文献。积液，胎儿疗法，胎儿新陈代谢）。结果仅限于系统评价，随机对照试验/对照临床试验，观察性研究和重要病例报告。从这些文章的书目中可以找到其他出版物。没有日期或语言限制。搜索会定期进行更新，并纳入到2012年5月的指南中。通过搜索卫生技术评估和卫生技术相关机构，临床实践指南集，临床试验注册机构以及国家和地区的网站，可以找到灰色（未出版）的文献。国际利益专业协会。益处，危害和费用：本指南教育读者有关非免疫性胎儿积水的原因及其产前咨询和管理。它还为非免疫性胎儿积液提供了一种标准化方法，强调了寻找产前可治疗的疾病和复发性遗传病因学的价值。价值：本文件中证据的质量使用加拿大预防性工作队报告中所述的标准进行评级。卫生保健（表1）。

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