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首页> 外文期刊>Molecular imaging and biology: MIB : the official publication of the Academy of Molecular Imaging >Qualitative and Quantitative Evaluation of Blob-Based Time-of-Flight PET Image Reconstruction in Hybrid Brain PET/MR Imaging
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Qualitative and Quantitative Evaluation of Blob-Based Time-of-Flight PET Image Reconstruction in Hybrid Brain PET/MR Imaging

机译：混合脑PET / MR成像中基于斑点的飞行时间PET图像重建的定性和定量评估

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摘要

Many neurological diseases affect small structures in the brain and, as such, reliable visual evaluation and accurate quantification are required. Recent technological developments made the clinical use of hybrid positron emission tomography/magnetic resonance (PET/MR) systems possible, providing both functional and anatomical information in a single imaging session. Nevertheless, there is a trade-off between spatial resolution and image quality (contrast and noise), which is dictated mainly by the chosen acquisition and reconstruction protocols. Image reconstruction algorithms using spherical symmetric basis functions (blobs) for image representation have a number of additional parameters that impact both the qualitative and quantitative image characteristics. Hence, a detailed investigation of the blob-based reconstruction characteristics using different parameters is needed to achieve optimal reconstruction results.
机译：许多神经系统疾病会影响大脑的小结构，因此，需要可靠的视觉评估和准确的量化。最近的技术发展使得在临床上使用混合正电子发射断层扫描/磁共振（PET / MR）系统成为可能，在单个成像会话中既提供功能信息又提供解剖信息。尽管如此，在空间分辨率和图像质量（对比度和噪声）之间还是要取舍，这主要取决于所选的采集和重建协议。使用球形对称基函数（blob）进行图像表示的图像重建算法具有许多其他参数，这些参数会影响定性和定量图像特征。因此，需要对使用不同参数的基于斑点的重建特性进行详细研究，以实现最佳重建结果。

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