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首页> 外文期刊>Movement disorders >Clinical characteristics of restless legs syndrome in end-stage renal failure and idiopathic RLS patients.
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Clinical characteristics of restless legs syndrome in end-stage renal failure and idiopathic RLS patients.

机译：终末期肾衰竭和特发性RLS患者的躁动腿综合征的临床特征。

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摘要

This study was done to identify the clinical characteristics of uremic restless legs syndrome (RLS). Consecutive uremic RLS patients (n = 15) and idiopathic RLS patients (iRLS; n = 20) were evaluated. The groups were compared with respect to their clinical course, subjective symptoms [using the Pittsburgh Sleep Quality Index (PSQI) and the International Restless Legs Syndrome Severity Scale (IRLS)], polysomnographic (PSG) variables, the results of the suggested immobilization test (SIT), and the drug doses used to treat RLS. The duration of the disorder was significantly shorter in the uremic RLS group than in the iRLS group. The PSQI and IRLS scores before treatment were higher in the uremic RLS group than in the iRLS group. The periodic leg movement index (PLM index) on PSG and the SIT index were also higher in the uremic RLS group (P < 0.001, respectively). The bromocriptine equivalent dose of dopaminergic agonists used to treat RLS was significantly higher in the uremic RLS group (P < 0.001). Uremic RLS appears to deteriorate faster and to become more severe than iRLS. Moreover, uremic RLS patients appear to have a decreased response to dopaminergic agonists.
机译：这项研究是为了确定尿毒症躁动性腿综合征（RLS）的临床特征。评价了连续尿毒症RLS患者（n = 15）和特发性RLS患者（iRLS; n = 20）。比较各组的临床历程，主观症状[使用匹兹堡睡眠质量指数（PSQI）和国际躁动腿综合征严重程度量表（IRLS）]，多导睡眠图（PSG）变量，建议的固定测试结果（ SIT），以及用于治疗RLS的药物剂量。尿毒症RLS组的疾病持续时间明显短于iRLS组。尿毒症RLS组治疗前的PSQI和IRLS评分高于iRLS组。在尿毒症RLS组中，PSG上的周期性腿部运动指数（PLM指数）和SIT指数也较高（分别为P <0.001）。在尿毒症RLS组中，用于治疗RLS的多巴胺能激动剂的溴隐亭当量相当高（P <0.001）。尿毒症RLS似乎比iRLS恶化得更快，并且变得更加严重。而且，尿毒症的RLS患者似乎对多巴胺能激动剂的反应降低。

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