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首页> 外文期刊>Movement disorders >Oral festination in Parkinson's disease: biomechanical analysis and correlation with festination and freezing of gait.
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Oral festination in Parkinson's disease: biomechanical analysis and correlation with festination and freezing of gait.

机译：帕金森氏病的口服预言：生物力学分析及其与步态预言和冻结的相关性。

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In Parkinson's disease (PD), festination corresponds to a tendency to speed up when performing repetitive movements. First described in gait (and then in handwriting and speech), festination is one of the most disabling axial symptoms. To establish the phenomenology of oral festination (OF) and the condition's potential links with other axial disorders, we submitted a simple, rhythmic, repetitive, vocal motor task to 40 PD patients and 20 controls. Forty-five percent of the 40 patients presented OF, which was strongly associated with gait festination but not with the severity of freezing of gait (FOG) or dysarthria. With respect to the two pathophysiological hypotheses that have been put forward, a possible link with tremor (as previously suggested in tapping) was not confirmed in this study and so, in view of the significant increase in variability observed, we conclude that OF shares the same pathophysiology as gait disorders.
机译：在帕金森氏病（PD）中，注视对应于执行重复运动时加速的趋势。首先在步态中描述（然后在手写和语音中描述），喜怒无常是最残酷的轴向症状之一。为了建立口腔功能的现象学（OF）及其与其他轴向疾病的潜在联系，我们向40名PD患者和20名对照进行了简单，有节奏，重复，发声的运动任务。 40名患者中有45％表现为OF，这与步态确定性密切相关，但与步态冻结（FOG）或构音障碍的严重程度无关。关于已提出的两个病理生理学假设，在本研究中未确认与震颤的可能联系（如先前在敲击中所建议的），因此，鉴于观察到的变异性显着增加，我们得出结论，OF共享与步态障碍相同的病理生理。

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