首页> 外文期刊>Mutation Research, C. Mutation Research Letters >GENOTOXIC EFFECTS OF DELTAMETHRIN IN THE MOUSE BONE MARROW MICRONUCLEUS ASSAY
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GENOTOXIC EFFECTS OF DELTAMETHRIN IN THE MOUSE BONE MARROW MICRONUCLEUS ASSAY

机译:地尔他命在小鼠骨髓微核试验中的遗传氧化作用

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摘要

The genotoxicity of deltamethrin was studied in Swiss albino male mice (five animals/group) using the bone marrow micronucleus assay. Deltamethrin (two i.p. injections, 30 h and 6 h before sample collection) was found to induce micronuclei at 162.5 and 300.0 mg/kg body weight. A lower dose (32.5 mg/kg body weight) failed to induce a significant increase in micronuclei over the control level.
机译:使用骨髓微核试验在瑞士的白化病雄性小鼠(五只动物/组)中研究了溴氰菊酯的遗传毒性。发现溴氰菊酯(两次腹膜内注射,分别在样品采集前30小时和6小时)以162.5和300.0 mg / kg体重诱导微核。较低剂量(32.5 mg / kg体重)未能诱导微核显着高于对照水平。

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