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首页> 外文期刊>Mutation Research, C. Mutation Research Letters >Distributions of nitropyrenes and mutagenicity in airborne participates collected with an Andersen sampler
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Distributions of nitropyrenes and mutagenicity in airborne participates collected with an Andersen sampler

机译：使用安徒生采样器收集的空中参与者中的硝基吡咯和致突变性分布

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摘要

Distributions of 1,3-dinitropyrene (1,3-DNP), 1,6-DNP, 1,8-DNP, 1-nitropyrene (1-NP) and mutagenicity in airborne particulates collected in downtown Kanazawa, Japan with an Andersen high-volume air sampler were examined. Mutagenicities of benzene-ethanol extract from particulates were determined by the Ames test using S. typhimurium strains without S9 mix, while concentrations of DNPs and 1-NP were determined by high-performance liquid chromatography (HPLC) using chemiluminescence detection. In the finest particulate fraction (smaller than 1.1 mum), 68% and 75% of the total mutagenicities were observed in TA98 and YG1024 strains, respectively. In the same fraction, 65-82% of three DNPs as well as 84% of 1-NP were observed. Mutagenic contributions of1,3-DNP, 1,6-DNP, 1,8-DNP and 1-NP in the extract were respectively 0.6,1.2,1.8 and 1.6% in the TA98 strain, and 2.5,5, 9 and 2.1% in the YG1024 strain.
机译：日本安达信高地市区金泽市收集的空气中微粒中1,3-二硝基py（1,3-DNP），1,6-DNP，1,8-DNP，1-硝基py（1-NP）的分布和致突变性检查了大容量的空气采样器。使用不含S9混合物的鼠伤寒沙门氏菌菌株通过Ames试验确定颗粒中苯乙醇提取物的致突变性，同时使用化学发光检测通过高效液相色谱（HPLC）测定DNP和1-NP的浓度。在最细的颗粒级分（小于1.1微米）中，分别在TA98和YG1024菌株中观察到总诱变性的68％和75％。在相同的分数中，观察到65-82％的三个DNP和84％的1-NP。提取物中1,3-DNP，1,6-DNP，1,8-DNP和1-NP的诱变贡献分别为TA98株的0.6、1.2、1.8和1.6％，以及2.5、5、9和2.1％在YG1024菌株中。

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