...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Mutation research. Genetic toxicology testing >USE OF TWO SHORT-TERM TESTS TO EVALUATE THE GENOTOXICITY OF RIVER WATER TREATED WITH DIFFERENT CONCENTRATION EXTRACTION PROCEDURES
【24h】

USE OF TWO SHORT-TERM TESTS TO EVALUATE THE GENOTOXICITY OF RIVER WATER TREATED WITH DIFFERENT CONCENTRATION EXTRACTION PROCEDURES

机译：两种短期试验用于评估不同浓度提取程序处理过的河流水的遗传毒性

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The genotoxicity of river water samples was evaluated by the Salmonella mutagenicity assay and by the microscreen phage-induction assay. Different processes of sample treatment were compared using the following assays: different volumes of a non-concentrated sample (direct method); concentrated sample fractionated into portions with acid, basic and neutral activity (liquid-liquid extraction method); sample submitted to extraction of volatile substances (volatile extraction method). Samples that were positive to the Salmonella assay by the direct concentration method lost this activity after liquid-liquid extraction. This difference was related to the loss of substances that volatilize during the extraction process. The study of volatile product concentrates confirmed the role of these compounds in inducing activity present in some samples. The microscreen phage-induction assay proved to be a good screening assay for genotoxic compounds present in small concentration in environmental samples. We conclude that, whenever possible, samples should be treated by the direct method in different volumes to prevent the loss of genotoxic substances.
机译：通过沙门氏菌诱变分析和微孔菌噬菌体诱导分析评估了河水样品的遗传毒性。使用以下测定法比较了不同的样品处理过程：不同体积的非浓缩样品（直接方法）;浓缩样品分为具有酸，碱性和中性活性的部分（液-液萃取法）;样品提交挥发性物质的提取（挥发性提取方法）。通过直接浓缩法对沙门氏菌测定呈阳性的样品在液-液萃取后失去了这种活性。这种差异与提取过程中挥发物质的损失有关。对挥发性产品浓缩物的研究证实了这些化合物在某些样品中诱导活性中的作用。经证明，微筛噬菌体诱导测定法是对环境样品中浓度低的遗传毒性化合物的良好筛选测定法。我们得出的结论是，应尽可能采用直接方法以不同的体积处理样品，以防止遗传毒性物质的损失。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号