ALTERNATE VIEW ON THERMAL STABILITY OF THE DNA DUPLEX

Kumar A

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ALTERNATE VIEW ON THERMAL STABILITY OF THE DNA DUPLEX

机译：关于DNA双链体热稳定性的替代观点

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A concept, based on the changes in internal pressure of water due to addition of salts, has been used to interpret the thermal stability of the DNA duplexes. Dependence of thermal stability of duplexes on the salt concentrations has also been described in terms of variations in the internal pressure of water observed in presence of ionic components. The thermal stabilities at high external pressures (up to 200 MPa) compared to those at atmospheric pressure are linearly related to the corresponding variations in internal pressures at several salt concentrations.

机译：基于添加盐引起的水内部压力变化的概念已被用来解释DNA双链体的热稳定性。还已经根据在离子组分存在下观察到的水的内部压力的变化描述了双链体的热稳定性对盐浓度的依赖性。与大气压力相比，高外部压力（最高200 MPa）下的热稳定性与几种盐浓度下内部压力的相应变化线性相关。

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《Biochemistry》 |1995年第40期|共5页
作者
Kumar A;
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正文语种 eng
中图分类生物化学;
关键词
Differential hydration; Pressure; Electrolyte; Water; Conformation; Temperature; Dependence; Polymers; Binding; Volumes;

机译：差分水合作用;压力;电解质;水;构象;温度;依赖性;聚合物;结合;体积;

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专利

1. ALTERNATE VIEW ON THERMAL STABILITY OF THE DNA DUPLEX [J] . Kumar A Biochemistry . 1995,第40期

机译：关于DNA双链体热稳定性的替代观点
2. CHIRAL CHEMICAL SYNTHESIS OF DNA CONTAINING (S)-9-(1,3-DIHYDROXY-2-PROPOXYMETHYL)GUANINE (DHPG) AND EFFECTS ON THERMAL STABILITY, DUPLEX STRUCTURE, AND THERMODYNAMICS OF DUPLEX FORMATION [J] . Marshalko SJ., Beardsley GP., Schweitzer BI. Biochemistry . 1995,第28期

机译：含（S）-9-（1,3-二羟基-2-丙氧基甲基）鸟嘌呤（DHPG）的DNA的手性化学合成及其对热稳定性，双链结构和双链形成热力学的影响
3. Two distinct thermal stabilities of DNA and enzymatic activities of DNase i in a multistep assembly with carbazole ligands: Different binding characteristics for duplex and quadruplex DNA [J] . Inukai N., Kawai T., Yuasa J. Chemistry: A European journal . 2013,第19期

机译：具有咔唑配体的多步组装中DNA的两个不同的热稳定性和DNase i的酶活性：双链和四链DNA的不同结合特性
4. Nucleic Acids Chemistry beyond the Watson-Crick Double Helix(57):Parameters for prediction of DNA duplex stabilities under thecrowding conditions [C] . Saptarshi Ghosh, ShuntaroTakahashi, Tatsuya Ohyama 日本化学会春季年会 . 2020

机译：核酸化学超出Watson-Cric Double Helix（57）：用于预测DNA双链稳定性的参数
5. Calorimetric and spectroscopic investigation of the thermally induced helix-coil transition in linear and closed duplex plasmid DNAs. [D] . Goldfarb, Daniel. 1994

机译：线性和封闭双链质粒DNA中热诱导的螺旋-螺旋跃迁的量热和光谱研究。
6. Influence of cisplatin intrastrand crosslinking on the conformation thermal stability and energetics of a 20-mer DNA duplex. [O] . N Poklar, D S Pilch, S J Lippard, 1996

机译：顺铂链内交联对20-mer DNA双链体的构象热稳定性和能级的影响。
7. Significantly Enhanced DNA Thermal Stability Resulting from Porphyrin H-Aggregate Formation in the Minor Grove of the Duplex [O] . Stephenson Adam W. I., Bomholt Niels, Partridge Ashton C., 2010

机译：双层小树林中卟啉H聚集体形成导致DNA热稳定性显着提高

ALTERNATE VIEW ON THERMAL STABILITY OF THE DNA DUPLEX

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