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首页> 外文期刊>Cancer: A Journal of the American Cancer Society >Perspectives on Barriers and Facilitators to Minority Recruitment for Clinical Trials Among Cancer Center Leaders, Investigators, Research Staff, and Referring Clinicians: Enhancing Minority Participation in Clinical Trials (EMPaCT)
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Perspectives on Barriers and Facilitators to Minority Recruitment for Clinical Trials Among Cancer Center Leaders, Investigators, Research Staff, and Referring Clinicians: Enhancing Minority Participation in Clinical Trials (EMPaCT)

机译：癌症中心负责人，研究人员，研究人员和推荐临床医生中针对少数族裔参加临床试验的障碍和促进者的观点：增强少数族裔对临床试验的参与（EMPaCT）

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BACKGROUND: The study of disparities in minority recruitment to cancer clinical trials has focused primarily on inquiries among minority populations. Yet very little is known about the perceptions of individuals actively involved in minority recruitment to clinical trials within cancer centers. Therefore, the authors assessed the perspectives of cancer center clinical and research personnel on barriers and facilitators to minority recruitment. METHODS: In total, 91 qualitative interviews were conducted at 5 US cancer centers among 4 stakeholder groups: cancer center leaders, principal investigators, research staff, and referring clinicians. All interviews were recorded and transcribed. Qualitative analyses of response data was focused on identifying prominent themes related to barriers and facilitators to minority recruitment. RESULTS: The perspectives of the 4 stakeholder groups were largely overlapping with some variations based on their unique roles in minority recruitment. Four prominent themes were identified: 1) racial and ethnic minorities are influenced by varying degrees of skepticism related to trial participation, 2) potential minority participants often face multilevel barriers that preclude them from being offered an opportunity to participate in a clinical trial, 3) facilitators at both the institutional and participant level potentially encourage minority recruitment, and 4) variation between internal and external trial referral procedures may limit clinical trial opportunities for racial and ethnic minorities. CONCLUSIONS: Multilevel approaches are needed to address barriers and optimize facilitators within cancer centers to enhance minority recruitment for cancer clinical trials.
机译：背景：针对癌症临床试验的少数族裔招聘差异的研究主要集中于少数族裔人群的查询。然而，人们对癌症中心内积极参与少数人募集到临床试验的个体知之甚少。因此，作者评估了癌症中心临床和研究人员对招募少数族裔的障碍和促进者的观点。方法：在美国的5个癌症中心的4个利益相关者群体中，总共进行了91次定性访谈：癌症中心负责人，首席研究人员，研究人员和转诊临床医生。所有采访均被记录并抄录。对反应数据进行定性分析的重点是确定与招募少数族裔的障碍和促进因素有关的突出主题。结果：这四个利益相关者群体的观点在很大程度上相互重叠，并因其在少数族裔招募中的独特作用而有所不同。确定了四个突出的主题：1）种族和少数民族受到与参与试验有关的不同程度的怀疑，2）潜在的少数族裔参与者经常面临多层次的障碍，使他们无法获得参加临床试验的机会，3）机构级和参与者级的促进者都可能鼓励少数族裔的招募，并且4）内部和外部试验转诊程序之间的差异可能会限制种族和少数民族的临床试验机会。结论：需要采取多层次的方法来解决障碍并优化癌症中心内的促进者，以增强少数人募集用于癌症临床试验。

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