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Farnesol induces apoptosis-like phenotype in the phytopathogenic fungus Botrytis cinerea

机译:法尼醇诱导植物病原真菌灰葡萄孢中的凋亡样表型

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This study demonstrates that the isoprenoid farnesol produces a toxic effect on the phytopathogenic fungus Botrytis cinerea in solid and liquid media. In solid media farnesol retarded 72 h the beginning of mycelial growth. Also, it was demonstrated that the toxic effect is due to farnesol triggers apoptosis in B. cinerea because ROS accumulation, DNA fragmentation and phosphatidylserine externalization were detected in farnesol-treated mycelium. Therefore, compounds that increase the intracellular farnesol or induce apoptosis could have a potential application as fungicide against B. cinerea.
机译:这项研究表明,类异戊二烯法尼醇在固态和液态介质中均对植物致病性真菌灰葡萄孢产生毒性作用。在固体培养基中,法尼醇延迟了72 h菌丝体生长的开始。此外,已证明毒性作用是由于法尼醇触发了灰葡萄孢菌的凋亡,因为在法尼醇处理的菌丝体中检测到ROS积累,DNA片段化和磷脂酰丝氨酸外在化。因此,增加细胞内法尼醇或诱导细胞凋亡的化合物可以作为抗灰葡萄孢的杀真菌剂。

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