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Diversity and evolution of ABC proteins in basidiomycetes

机译：担子菌中ABC蛋白的多样性和进化

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摘要

ABC proteins constitute one of the largest families of proteins. They are implicated in wide variety of cellular processes ranging from ribosome biogenesis to multidrug resistance. With the advance of fungal genomics, the number of known fungal ABC proteins increases rapidly but the information on their biological functions remains scarce. In this work we extended the previous analysis of fungal ABC proteins to include recently sequenced species of basidiomycetes. We performed an identification and initial cataloging of ABC proteins from 23 fungal species representing 10 orders within class Agaricomycotina. We identified more than 1000 genes coding for ABC proteins. Comparison of sets of ABC proteins present in basidiomycetes and ascomycetes revealed the existence of two groups of ABC proteins specific for basidiomycetes. Results of survey should contribute to the better understanding of evolution of ABC proteins in fungi and support further experimental work on their characterization.
机译：ABC蛋白质构成最大的蛋白质家族之一。它们与从核糖体生物发生到多药耐药性的多种细胞过程有关。随着真菌基因组学的发展，已知的真菌ABC蛋白的数量迅速增加，但有关其生物学功能的信息仍然很少。在这项工作中，我们扩展了以前对真菌ABC蛋白的分析，以包括最近测序的担子菌种。我们进行了鉴定和初步分类，从23种真菌种类的ABC蛋白代表了Agaricomycotina类中的10个订单。我们确定了1000多个编码ABC蛋白的基因。比较担子菌和子囊菌中存在的ABC蛋白的集合，发现存在两组对担子菌特异的ABC蛋白。调查结果应有助于更好地了解真菌中ABC蛋白的进化，并支持对其表征进行进一步的实验工作。

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