• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Mycologia >Metabolite diversity in the plant pathogen Alternaria brassicicola: factors affecting production of brassicicolin A, depudecin, phomapyrone A and other metabolites
【24h】

Metabolite diversity in the plant pathogen Alternaria brassicicola: factors affecting production of brassicicolin A, depudecin, phomapyrone A and other metabolites

机译：植物病原体链格孢菌中的代谢物多样性：影响芸苔素A，地普丁，磷甲酮A和其他代谢物生产的因素

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

A systematic investigation of the metabolites of Alternaria brassicicola produced under various culture conditions is reported. The phytotoxin brassicicolin A is produced in significantly larger amounts in potato dextrose broth than in minimal medium cultures. In general an increase in the incubation temperature of cultures 23-30 C increases the production of brassicicolin A but decreases depudecin production. Reducing or eliminating nitrate from culture media or adding ammonium chloride increases the production of brassicicolin A at 30 C, depudecin at 23 C and alpha-acetylorcinol at either temperature, suggesting that nitrogen represses their biosynthesis. Siderophores are detected in cultures of A. brassicicola containing low and high ferric ion concentrations. The metabolites alpha-acetylorcinol and tyrosol are isolated for the first time from cultures of A. brassicicola, and alpha-acetylorcinol is synthesized in four steps and 36% overall yield. Only brassicicolin A and no other isolated metabolites, including depudecin and phomapyrone A, display phytotoxicity on leaves of Brassica species (up to 5.0 mM). Epigenetic modifiers, 5-azacitidin (5-AZA), suberoylanilide hydroxamic acid (SAHA) and suberoyl bis-hydroxamic acid (SBHA) do not affect the metabolite profiles of liquid cultures of this fungal pathogen.
机译：对在不同培养条件下产生的链格孢菌的代谢产物进行了系统的研究。与最低限度的培养基培养相比，马铃薯葡萄糖肉汤中产生的植物毒素油菜素青霉素A的量要大得多。通常，培养物温育温度的升高23-30℃增加了油菜素甲A的产量，但降低了氘代癸丁素的产量。减少或消除培养基中的硝酸盐或添加氯化铵可提高30°C时的油菜素A，23°C时的十氢癸内酯和任一温度下的α-乙酰基丁二酚的产量，表明氮抑制了它们的生物合成。在含有低铁离子浓度和高铁离子浓度的油菜曲霉培养物中检测到铁载体。首次从油菜曲霉的培养物中分离出代谢物α-乙酰基蓖麻酚和酪醇，并且通过四个步骤合成了α-乙酰基蓖麻酚，总收率为36％。只有芸苔素A和其他分离出的代谢物，包括地精蛋白和磷吡喃酮A，在芸苔属植物的叶片上显示出植物毒性（最高达5.0 mM）。表观遗传修饰剂5-氮杂蝶呤（5-AZA），亚磺酰苯胺异羟肟酸（SAHA）和亚磺酰双异羟肟酸（SBHA）不会影响该真菌病原体液体培养物的代谢产物谱。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号