Monoalleleic transcription of the insulin-like growth factor-II gene (Igf2) in chick embryos.

Koski LB; Sasaki E; Roberts RD; Gibson J; Etches RJ

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Monoalleleic transcription of the insulin-like growth factor-II gene (Igf2) in chick embryos.

机译：雏鸡胚胎中胰岛素样生长因子II基因（Igf2）的单等位基因转录。

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A polymorphism in the igf2 gene of chickens was identified using NlaIII (GenBank accession number AF218827). In some embryos, the igf2 alleles were expressed monoallelically from either maternal or paternal alleles. These data demonstrate that genomic imprinting is not confined to mammals and suggest that genomic imprinting evolved at an early stage of vertebrate evolution. The observations that the igf2 gene is imprinted in a minority of embryos suggest that the imprinting in birds is unrelated toembryonic growth. Genome imprinting may provide opportunities for evolution of genes in a non-expressed state. In poultry breeding, the presence of imprinted genes may make a major contribution to unequal performance in reciprocal matings between commercial lines.

机译：使用NlaIII（GenBank登录号AF218827）鉴定了鸡的igf2基因多态性。在某些胚胎中，igf2等位基因由母本或父本等位基因单等位表达。这些数据表明基因组印记不仅限于哺乳动物，并且表明基因组印记是在脊椎动物进化的早期阶段进化的。 igf2基因在少数胚胎中有印记的观察结果表明，鸟类中的印记与胚胎生长无关。基因组印迹可能会为非表达状态的基因进化提供机会。在家禽育种中，印迹基因的存在可能是导致商品系之间相互交配表现不均的主要原因。

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《Molecular reproduction and development》 |2000年第3期|共8页
作者
Koski LB; Sasaki E; Roberts RD; Gibson J; Etches RJ;
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正文语种 eng
中图分类分子生物学;
关键词
insulin like growth factor; embryos; alleles; genes; genomes; genomic imprinting; genetic polymorphism; biotechnology; poultry; fowls;

机译：胰岛素样生长因子;胚胎;等位基因;基因;基因组;基因组印迹;遗传多态性;生物技术;禽;禽;

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1. Monoalleleic transcription of the insulin-like growth factor-II gene (Igf2) in chick embryos. [J] . Koski LB, Sasaki E, Roberts RD, Molecular reproduction and development . 2000,第3期

机译：雏鸡胚胎中胰岛素样生长因子II基因（Igf2）的单等位基因转录。
2. Loss of imprinting of insulin-like growth factor-II (IGF2) gene in distinguishing specific biologic subtypes of Wilms tumor. [J] . Ravenel JD, Broman KW, Perlman EJ, Journal of the National Cancer Institute . 2001,第22期

机译：胰岛素样生长因子-II（IGF2）基因的印迹在区分Wilms肿瘤的特定生物学亚型中丢失。
3. Insulin-like growth factor-II regulates bone sialoprotein gene transcription [J] . Choe Jin, Sasaki Yoko, Zhou Liming, Odontology . 2016,第3期

机译：胰岛素样生长因子-II调节骨唾液蛋白基因转录
4. FUNCTION OF INSULIN-LIKE GROWTH FACTOR 2 (IGF2) IN THE DIFFERENTIATION OF TROUT SATELLITE CELLS [C] . Gabillard JC, Seiliez I, Sabin N Annual Meeting of the European Aquaculture Society . 2013

机译：胰岛素样生长因子2（IGF2）在鳟鱼卫星细胞分化中的作用
5. Insulin-like growth factor-II (IGF2) gene of zebrafish and its use as a biogenetic marker for the assay of epigenetic toxin exposure. [D] . Alazzabi, Mufida. 2004

机译：斑马鱼的胰岛素样生长因子-II（IGF2）基因及其作为生物遗传标记用于表观遗传毒素暴露的测定。
6. Identification of a novel transcription unit in the human insulin-like growth factor-II gene. [O] . K Ikejiri, T Wasada, K Haruki, 1991

机译：人胰岛素样生长因子-II基因中的新型转录单位的鉴定。
7. Re: Loss of Imprinting of Insulin-Like Growth Factor-II (IGF2) Gene in Distinguishing Specific Biologic Subtypes of Wilms Tumor [O] . I. M. Morison 2002

机译：Re：在区分胰肿瘤的特异性生物亚型中，胰岛素样生长因子-II（IGF2）基因的印迹丧失

Monoalleleic transcription of the insulin-like growth factor-II gene (Igf2) in chick embryos.

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