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首页> 外文期刊>Cancer: A Journal of the American Cancer Society >Yoga for persistent fatigue in breast cancer survivors: A randomized controlled trial
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Yoga for persistent fatigue in breast cancer survivors: A randomized controlled trial

机译：瑜伽对乳腺癌幸存者持续疲劳的影响：一项随机对照试验

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BACKGROUND: Cancer-related fatigue afflicts up to 33% of breast cancer survivors, yet there are no empirically validated treatments for this symptom. METHODS: The authors conducted a 2-group randomized controlled trial to determine the feasibility and efficacy of an Iyengar yoga intervention for breast cancer survivors with persistent post-treatment fatigue. Participants were breast cancer survivors who had completed cancer treatments (other than endocrine therapy) at least 6 months before enrollment, reported significant cancer-related fatigue, and had no other medical conditions that would account for fatigue symptoms or interfere with yoga practice. Block randomization was used to assign participants to a 12-week, Iyengar-based yoga intervention or to 12 weeks of health education (control). The primary outcome was change in fatigue measured at baseline, immediately post-treatment, and 3 months after treatment completion. Additional outcomes included changes in vigor, depressive symptoms, sleep, perceived stress, and physical performance. Intent-to-treat analyses were conducted with all randomized participants using linear mixed models. RESULTS: Thirty-one women were randomly assigned to yoga (n = 16) or health education (n = 15). Fatigue severity declined significantly from baseline to post-treatment and over a 3-month follow-up in the yoga group relative to controls (P =.032). In addition, the yoga group had significant increases in vigor relative to controls (P =.011). Both groups had positive changes in depressive symptoms and perceived stress (P <.05). No significant changes in sleep or physical performance were observed. CONCLUSIONS: A targeted yoga intervention led to significant improvements in fatigue and vigor among breast cancer survivors with persistent fatigue symptoms.
机译：背景：与癌症相关的疲劳困扰着多达33％的乳腺癌幸存者，但目前尚无针对这种症状的经实践验证的治疗方法。方法：作者进行了2组随机对照试验，以确定Iyengar瑜伽干预对患有持续治疗后疲劳的乳腺癌幸存者的可行性和有效性。参加研究的乳腺癌幸存者在入组前至少6个月完成了癌症治疗（内分泌疗法除外），报告了与癌症相关的明显疲劳，并且没有其他会导致疲劳症状或干扰瑜伽练习的医学状况。使用分组随机分配法将参与者分配到基于艾扬格的12周瑜伽干预或12周的健康教育（对照）中。主要结果是在基线，治疗后立即和治疗完成后3个月测得的疲劳变化。其他结果包括活力变化，抑郁症状，睡眠，感觉到的压力和身体机能。使用线性混合模型对所有随机参与者进行意向治疗分析。结果：31名妇女被随机分配到瑜伽（n = 16）或健康教育（n = 15）中。与对照组相比，瑜伽组从基线到治疗后以及经过3个月的随访，疲劳严重程度均显着下降（P = .032）。此外，与对照组相比，瑜伽组的活力显着提高（P = .011）。两组的抑郁症状和感觉到的压力都有积极的变化（P <.05）。没有观察到睡眠或身体机能的明显变化。结论：有针对性的瑜伽干预可显着改善患有持续疲劳症状的乳腺癌幸存者的疲劳和活力。

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