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首页> 外文期刊>Korean Journal of Microbiology and Biotechnology >Comparative Study on the Antimicrobial Activity of Glycyrrhiza uralensis and Glycyrrhiza glabra Extracts with Various Countries of Origin as Natural Antiseptics
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Comparative Study on the Antimicrobial Activity of Glycyrrhiza uralensis and Glycyrrhiza glabra Extracts with Various Countries of Origin as Natural Antiseptics

机译：甘草与甘草提取物与天然来源的天然抗菌剂的抑菌活性比较研究

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摘要

The aim of this study was to evaluate the antimicrobial activities of Glycyrrhiza uralensis and Glycyrrhiza glabra extracts with various countries of origin. Three samples of licorice with various origins (Korea, China, and Uzbekistan) were evaluatedfor their antimicrobial activities against six skin microflora. The bioassay applied for determining the antimicrobial effects included the disc diffusion assay, minimum inhibitory concentration, and challenge test. The ethyl acetate fractions of G. uralensis and G. glabra extracts showed significant antimicrobial activities against two gram-positive (Bacillus subtilis, Propionibacterium acnes) and two gram-negative (Escherichia coli, Pseudomonas aeruginosa) bacteria. These samples had much more intensive antimicrobial activities than synthetic preservatives on B. subtilis, P. acnes, and P. aeruginosa, especially. Korean licorice showed the highest antimicrobial activity amongst the samples tested. In view of the observed inhibitory features of these Guralensis and G glabra extracts, it is suggested that they could be used as natural antiseptics against bacterial contamination in cosmetics and foods, instead of the common synthetic preservatives currently employed.
机译：这项研究的目的是评估不同来源的甘草和甘草提取物的抗菌活性。评估了三个不同来源的甘草样品（韩国，中国和乌兹别克斯坦）对六种皮肤微生物的抗菌活性。用于确定抗微生物作用的生物测定法包括椎间盘扩散测定法，最小抑菌浓度和激发试验。 G.uralensis和G.glabra提取物的乙酸乙酯级分显示出对两种革兰氏阳性菌（枯草芽孢杆菌，痤疮丙酸杆菌）和两种革兰氏阴性菌（大肠杆菌，铜绿假单胞菌）具有显着的抗菌活性。这些样品尤其对枯草芽孢杆菌，痤疮丙酸杆菌和铜绿假单胞菌具有比合成防腐剂更强的抗菌活性。在测试的样品中，韩国甘草显示出最高的抗菌活性。鉴于观察到的这些Guralensis和G glabra提取物的抑制特性，建议将它们用作化妆品和食品中天然细菌的抗菌剂，以代替细菌污染，代替目前使用的常用合成防腐剂。

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