...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Korean Journal of Microbiology and Biotechnology >Anti-wrinkling Effects of Juniperus rigida Sied.
【24h】

Anti-wrinkling Effects of Juniperus rigida Sied.

机译：杜松的抗皱作用。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Human skin is constantly exposed to environmental conditions such as UV rays, polluted air, and chemical products. UV rays, in particular, affect skin in many ways causing wrinkles, fine wrinkles, rough skin, and xeroderma through a skin aging process. The purpose of this study was to investigate the anti-wrinkling effect of Juniperus rigida Sieb., derived from a common cedar tree found the world over. Measuring the elastase to investigate wrinkling efficacy, it was shown that at a concentration level of 1,000 ug/ml of the two extracts, the water extract exhibited a lower than 10% inhibition activity, while the ethanol extract exhibited a 68.5% inhibition activity. Collagenase inhibition activity in the water extract and ethanol extract were 44.9% in the former and 97.2% in the latter extract, which in the case of the ethanol extract, is similar to ascorbic acid (99.6%). Moreover, measuring the biosynthesis of collagen by fibroblast, a concentration level of 50 ug/ml of ethanol extract produced 151.52% of biosyn-thetic promotion, proving that the ethanol extract acts as a superb anti-wrinkling agent. The result of an investigation conducted on the influence of the ethanol extract on MMP-1 caused by UVA showed that at a concentration level of 100 ug/ml of the ethanol extract of J. rigida Sieb a 67.1% inhibition activity was noted. At a concentration level of 50 ug/ml of the ethanol extract of J. ngida Sieb a 35% and 39% inhibition ratio to MMP-1 protein and mRNA were observed respectively, therebyrestraining the appearance of the collagen breakdown enzyme MMP-1 and wrinkle creation by skin photo-aging.
机译：人体皮肤不断暴露于紫外线，污染的空气和化学产品等环境条件下。紫外线尤其会以多种方式影响皮肤，从而在皮肤老化过程中引起皱纹，细纹，粗糙的皮肤和干性皮肤。这项研究的目的是研究源自世界各地的普通雪松的杜松僵尸的抗皱作用。测量弹性蛋白酶以研究皱纹功效，显示出在两种提取物的浓度为1,000ug / ml的情况下，水提取物表现出低于10％的抑制活性，而乙醇提取物表现出68.5％的抑制活性。水提取物和乙醇提取物中的胶原酶抑制活性在前者中为44.9％，在后者提取物中为97.2％，在乙醇提取物的情况下，与抗坏血酸相似（99.6％）。此外，通过成纤维细胞测量胶原的生物合成，浓度为50μg/ ml的乙醇提取物产生了151.52％的生物合成促进作用，证明了乙醇提取物起着极好的抗皱剂的作用。关于乙醇提取物对由UVA引起的MMP-1的影响的研究结果表明，在浓度为100ug / ml的僵硬耶氏酵母的乙醇提取物中，发现了67.1％的抑制活性。在浓度为50 ug / ml的中华按蚊的乙醇提取物中，分别观察到对MMP-1蛋白和mRNA的抑制率分别为35％和39％，从而抑制了胶原分解酶MMP-1和皱纹的出现。通过皮肤光老化创造。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号