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Vertically aligned carbon nanofiber arrays record electrophysiological signals from hippocampal slices

机译:垂直排列的碳纳米纤维阵列记录海马切片的电生理信号

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摘要

Vertically aligned carbon nanofiber (VACNF) electrode arrays were tested for their potential application in recording neuro-electrophysiological activity. We report, for the first time, stimulation and extracellular recording of spontaneous and evoked neuroelectrical activity in organotypic hippocampal slice cultures with ultramicroelectrode VACNF arrays. Because the electrodes are carbon-based, these arrays have potential advantages over metal electrodes and could enable a variety of future applications as precise, informative, and biocompatible neural interfaces.
机译:测试了垂直排列的碳纳米纤维(VACNF)电极阵列在记录神经电生理活动中的潜在应用。我们首次报告了用超微电极VACNF阵列对有机型海马切片培养物中的自发性和诱发性神经电活动的刺激和细胞外记录。由于电极是基于碳的,因此这些阵列具有优于金属电极的潜在优势,并且可以实现各种将来的应用,例如精确,信息丰富且生物相容的神经接口。

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