Real-time imaging of astrocyte response to quantum dots: In vivo screening model system for biocompatibility of nanoparticles

Maysinger D; Behrendt M; Lalancette-Herbert M; Kriz J

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Real-time imaging of astrocyte response to quantum dots: In vivo screening model system for biocompatibility of nanoparticles

机译：星形细胞对量子点反应的实时成像：纳米粒子生物相容性的体内筛选模型系统。

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Astrocytes are the principle macroglial brain cells. They are activated by different stressors and brain injuries. Quantum dots (QDs) can cause oxidative stress. This study shows a real-time imaging of primary cortical cultures and assessment of QD-induced activation of astrocytes in the brains of transgenic mice with the luciferase gene driven by the murine astrocyte promoter. This approach may be widely applicable for assessing the astroglia/tissue response to nanoparticles in live animals.

机译：星形胶质细胞是主要的神经胶质细胞。它们由不同的压力源和脑损伤激活。量子点（QD）会引起氧化应激。这项研究显示了原代皮层培养物的实时成像，并评估了由鼠星形胶质细胞启动子驱动的荧光素酶基因对转基因小鼠大脑中QD诱导的星形胶质细胞活化的作用。该方法可能广泛适用于评估对活动物中纳米颗粒的星形胶质细胞/组织反应。

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《Nano letters》 |2007年第8期|共8页
作者
Maysinger D; Behrendt M; Lalancette-Herbert M; Kriz J;
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正文语种 eng
中图分类特种结构材料;
关键词
CELLS; MICELLES; NANOCARRIERS; NEUROSCIENCE; ACTIVATION; PROBES; DAMAGE;

机译：细胞;胶束;纳米载体;神经科学;活化;问题;损伤;

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1. Real-time imaging of astrocyte response to quantum dots: In vivo screening model system for biocompatibility of nanoparticles [J] . Maysinger D, Behrendt M, Lalancette-Herbert M, Nano letters . 2007,第8期

机译：星形细胞对量子点反应的实时成像：纳米粒子生物相容性的体内筛选模型系统。
2. Biocompatible fluorescent carbon quantum dots prepared from beetroot extract for in vivo live imaging in C-elegans and BALB/c mice [J] . Singh Vikram, Rawat Kundan S., Mishra Shachi, Journal of Materials Chemistry, B. materials for biology and medicine . 2018,第20期

机译：从C-elegans和BALB / C小鼠中体内活影制备的生物相容性荧光碳量子点。
3. 'Green'-synthesized near-infrared PbS quantum dots with silica-PEG dual-layer coating: Ultrastable and biocompatible optical probes for in vivo animal imaging [J] . Wang D., Qian J., Cai F., Nanotechnology . 2012,第24期

机译：具有二氧化硅-PEG双层涂层的“绿色”合成的近红外PbS量子点：用于体内动物成像的超稳定且生物相容的光学探针
4. Fluorescent quantum dot as model imaging probe for studying plant uptake, systemic mobility, localization in plant tissue and potential fate of ultra-small nanoparticles [C] . Smruti Das, Jeremy Tharkur, Laurene Tetard, Biotech, biomaterials and biomedical . 2016

机译：荧光量子点作为模型成像探针，用于研究植物吸收，系统迁移率，植物组织中的定位以及超小纳米粒子的潜在命运
5. The Optical Response of Strongly Coupled Quantum Dot- Metal Nanoparticle Hybrid Systems. [D] . Artuso, Ryan Domenick. 2012

机译：强耦合量子点-金属纳米粒子杂化系统的光学响应。
6. CLAVATA3 Dodecapeptide Modified CdTe Nanoparticles: A Biocompatible Quantum Dot Probe for In Vivo Labeling of Plant Stem Cells [O] . Guanghui Yu, Yanping Tan, Xiangzhu He, 2010

机译：CLAVATA3十二肽修饰的CdTe纳米粒子：用于植物干细胞体内标记的生物相容性量子点探针。
7. Real-Time Imaging of Astrocyte Response to Quantum Dots: In Vivo Screening Model System for Biocompatibility of Nanoparticles [O] . -1

机译：量子点对天线胶质细胞反应的实时成像：在纳米粒子生物相容性的体内筛选模型系统中

Real-time imaging of astrocyte response to quantum dots: In vivo screening model system for biocompatibility of nanoparticles

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