Self-aligned immobilization of proteins utilizing PEG patterns

Lee LM; Heimark RL; Baygents JC; Zohar Y

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Self-aligned immobilization of proteins utilizing PEG patterns

机译：利用PEG模式自对准固定化蛋白质

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摘要

A novel self-aligned method to selectively immobilize proteins oil a silicon dioxide surface is developed in conjunction with a standard lift-off patterning technique of a PEG layer. The approach is designed to photolithographically pattern regions that specifically bind target proteins and particles, surrounded by regions that suppress non-specific attachment of blo-species. The physical and biological properties of the derivatized surfaces at the end of the fabrication process are characterized.

机译：结合PEG层的标准剥离图案技术，开发了一种新型的自对准方法，可选择性地在二氧化硅表面上固定化蛋白质。该方法旨在对特定结合目标蛋白和颗粒的区域进行光刻图案化，并在周围区域中抑制blo种的非特异性附着。在制造过程结束时，表征了衍生化表面的物理和生物学特性。

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《Nanotechnology》 |2006年第4期|共5页
作者
Lee LM; Heimark RL; Baygents JC; Zohar Y;
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正文语种 eng
中图分类一般工业技术;
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PLASMA;

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专利

1. Self-aligned immobilization of proteins utilizing PEG patterns [J] . Lee LM, Heimark RL, Baygents JC, Nanotechnology . 2006,第4期

机译：利用PEG模式自对准固定化蛋白质
2. Measuring self-aligned quadruple patterning pitch walking with scatterometry-based metrology utilizing virtual reference [J] . Taher Kagalwala, Alok Vaid, Sridhar Mahendrakar, Journal of microanolithography, MEMS, and MOEMS . 2016,第4期

机译：使用基于虚拟参考的基于散射的计量学来测量自对准四重图案俯仰行走
3. Ultrathin coatings from isocyanate terminated star PEG prepolymers: Patterning of proteins on the layers [J] . Groll J, Haubensak W, Ameringer T, Langmuir: The ACS Journal of Surfaces and Colloids . 2005,第7期

机译：异氰酸酯封端的星形PEG预聚物制成的超薄涂层：层上蛋白质的图案
4. Self-Aligned Immobilization of Proteins on Silicon Dioxide Surfaces [C] . Lap Man Lee, Ronald L. Heimark, James C. Baygents International Symposium on Runaway Reactions, Pressure Relief Design and Effluent Handling American Institute of Chemical Engineers/American Chemical Society Management Conference . 2005

机译：二氧化硅表面上蛋白质的自我对准固定
5. Examination of the effect of PEG-rich matrices in multi drug resistance-associated protein (MRP) and multi drug resistance (MDR) substrates transport utilizing the CaCo-2 cell model. [D] . Santos-Roman, Nilmarie. 2008

机译：利用CaCo-2细胞模型检查富含PEG的基质在多药耐药相关蛋白（MRP）和多药耐药（MDR）底物转运中的作用。
6. Immobilization Patterns and Dynamics of Acetate-Utilizing Methanogens Immobilized in Sterile Granular Sludge in Upflow Anaerobic Sludge Blanket Reactors [O] . Jens Ejbye Schmidt, Birgitte Kjær Ahring 1999

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7. Immobilization Patterns and Dynamics of Acetate-Utilizing Methanogens Immobilized in Sterile Granular Sludge in Upflow Anaerobic Sludge Blanket Reactors [O] . Jens Ejbye Schmidt, Birgitte Kjær Ahring 1999

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Self-aligned immobilization of proteins utilizing PEG patterns

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