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Labelling of silica microspheres with fluorescent lanthanide-doped LaF_3 nanocrystals

机译:荧光镧掺杂的LaF_3纳米晶体对二氧化硅微球的标记

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摘要

Fluorescent microspheres have been demonstrated to be useful in a variety of biological applications. Fluorescent silica or polymer microspheres have been produced by incorporation of chromophores into the microspheres, which usually produces microspheres with nonuniform sizes and reduced fluorescence. Here we present a simple and straightforward method to produce silica microspheres with fluorescent lanthanide-doped LaF_3 nanocrystals grown on the surface. LaF_3 nanocrystals are in situ grown on silica microspheres of different sizes to form a raspberry-like structure. The microspheres exhibit strong fluorescence and the colour could be altered by changing the lanthanide ions doped in LaF_3 nanocrystals.
机译:荧光微球已被证明可用于多种生物学应用。通过将发色团掺入微球中来生产荧光二氧化硅或聚合物微球,其通常产生尺寸不均匀且荧光降低的微球。在这里,我们提出了一种简单而直接的方法来生产二氧化硅微球,该二氧化硅微球具有生长在表面的荧光镧掺杂的LaF_3纳米晶体。 LaF_3纳米晶体在不同大小的二氧化硅微球上原位生长,形成树莓状结构。微球具有很强的荧光性,可以通过改变LaF_3纳米晶体中掺杂的镧系元素离子来改变颜色。

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