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Microheater based on magnetic nanoparticle embedded PDMS

机译:基于磁性纳米颗粒嵌入式PDMS的微加热器

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摘要

A microheater was established by embedding magnetic nanoparticles into PDMS (MNP-PDMS). MNP-PDMS generated heat under an AC magnetic field and the temperature was controlled by varying the magnetic particle content and the magnetic field intensity. In this study, the MNP-PDMS chip was demonstrated to amplify the target DNA (732 bp) with >90% efficiency compared to the conventional PCR thermocycler, and exhibited good performance in regards to temperature control. This system holds great promise for reliably controlling the temperature of thermal processes on an integrated microchip platform for biochemical applications.
机译:通过将磁性纳米粒子嵌入PDMS(MNP-PDMS)中来建立微型加热器。 MNP-PDMS在交流磁场下产生热量,并通过改变磁性颗粒含量和磁场强度来控制温度。在这项研究中,与传统的PCR热循环仪相比,MNP-PDMS芯片被证明能以大于90%的效率扩增目标DNA(732 bp),并且在温度控制方面表现出良好的性能。该系统具有在生化应用的集成微芯片平台上可靠地控制热处理温度的巨大希望。

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