Network single-walled carbon nanotube biosensors for fast and highly sensitive detection of proteins

Hu P.; Zhang J.; Wen Z.; Zhang C.

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Network single-walled carbon nanotube biosensors for fast and highly sensitive detection of proteins

机译：网络单壁碳纳米管生物传感器，用于蛋白质的快速和高灵敏度检测

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Detection of proteins is powerfully assayed in the diagnosis of diseases. A strategy for the development of an ultrahigh sensitivity biosensor based on a network single-walled carbon nanotube (SWNT) field-effect transistor (FET) has been demonstrated. Metallic SWNTs (m-SWNTs) in the network nanotube FET were selectively removed or cut via a carefully controlled procedure of electrical break-down (BD), and left non-conducting m-SWNTs which magnified the Schottky barrier (SB) area. This nanotube FET exhibited ultrahigh sensitivity and fast response to biomolecules. The lowest detection limit of 0.5pM was achieved by exploiting streptavidin (SA) or a biotin/SA pair as the research model, and BD-treated nanotube biosensors had a 2 × 10~4-fold lower minimum detectable concentration than the device without BD treatment. The response time is in the range of 0.3-3min.

机译：蛋白质的检测在疾病诊断中得到了有力的检测。已经证明了开发基于网络单壁碳纳米管（SWNT）场效应晶体管（FET）的超高灵敏度生物传感器的策略。通过小心控制的电击穿（BD）程序，有选择地去除或切割网络纳米管FET中的金属SWNT（m-SWNT），并留下不导电的m-SWNT，这会放大肖特基势垒（SB）区域。这种纳米管FET表现出超高的灵敏度和对生物分子的快速响应。通过使用链霉亲和素（SA）或生物素/ SA对作为研究模型，实现了最低检测限0.5pM，并且BD处理的纳米管生物传感器的最低可检测浓度比没有BD的设备低2×10〜4倍治疗。响应时间在0.3-3分钟范围内。

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《Nanotechnology》 |2011年第33期|共7页
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Hu P.; Zhang J.; Wen Z.; Zhang C.;
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1. Network single-walled carbon nanotube biosensors for fast and highly sensitive detection of proteins [J] . Hu P., Zhang J., Wen Z., Nanotechnology . 2011,第33期

机译：网络单壁碳纳米管生物传感器，用于蛋白质的快速和高灵敏度检测
2. Single-walled carbon nanotube field-effect transistors with graphene oxide passivation for fast, sensitive, and selective protein detection [J] . Chang J., Mao S., Zhang Y., Biosensors & Bioelectronics: The International Journal for the Professional Involved with Research, Technology and Applications of Biosensers and Related Devices . 2013,第Null期

机译：具有氧化石墨烯钝化的单壁碳纳米管场效应晶体管，用于快速，灵敏和选择性的蛋白质检测
3. Highly sensitive room temperature carbon monoxide detection using SnO _2 nanoparticle-decorated semiconducting single-walled carbon nanotubes [J] . Zhang Y., Cui S., Chang J., Nanotechnology . 2013,第2期

机译：SnO _2纳米粒子修饰的半导体单壁碳纳米管对高灵敏度室温一氧化碳的检测
4. HIGHLY SENSITIVE DETECTION OF ORGANOPHOSPHORUS BASED ON THE NETWORK OF SEMICONDUCTING SINGLE-WALLED CARBON NANOTUBES [C] . Liangming Wei, Zhenqing Dai, Haiyan Chen Annual World Conference on Carbon . 2011

机译：基于半导体单壁碳纳米管网络的有机磷的高敏感性检测
5. Bio-templated conducting polymer nanostructures for sensitive detection and flexible electronics: I. DNA-templated polyaniline nanowire for fast detection of chemicals. II. A self-doped polyaniline/carbon nanotube nanocomposite for ultrasensitive biosensors and flexible electronics [D] . Ma, Yufeng 2007

机译：用于灵敏检测和柔性电子的生物模板导电聚合物纳米结构：I. DNA模板聚苯胺纳米线，用于快速检测化学物质。二。用于超灵敏生物传感器和柔性电子产品的自掺杂聚苯胺/碳纳米管纳米复合材料
6. Biosensor based on tyrosinase immobilized on a single-walled carbon nanotube-modifiedglassy carbon electrode for detection of epinephrine [O] . Irina Mirela Apetrei, Constantin Apetrei 2013

机译：基于酪氨酸酶的生物传感器固定在单壁碳纳米管上玻碳电极可检测肾上腺素
7. Network Single-Walled Carbon Nanotube-Field Effect Transistors (SWNT-FETs) with Increased Schottky Contact Area for Highly Sensitive Biosensor Applications [O] . -1

机译：网络单壁碳纳米管场效应晶体管（SWNT-FET），具有增加的肖特基接触面积，用于高敏感的生物传感器应用

Network single-walled carbon nanotube biosensors for fast and highly sensitive detection of proteins

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