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Transport of single cells using an actin bundle-myosin bionanomotor transport system

机译:使用肌动蛋白束-肌球蛋白仿生运动系统的单细胞运输

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摘要

The potential of using actin bundles for the transport of liposomes and single cells across myosin-coated surfaces is investigated. Compared to that observed with filamentous actin, the liposome transport using actin bundles was more linear in nature and able to occur over longer distances. Bundles, but not filamentous actin, were capable of moving single cells. Cargo unloading from bundles was achieved by incubation with Triton X-100. These data suggest that actin bundling may improve the ability of the myosin motor system for nanotransport applications.
机译:研究了使用肌动蛋白束在肌球蛋白包被的表面上转运脂质体和单细胞的潜力。与用丝状肌动蛋白观察到的相比,使用肌动蛋白束的脂质体转运在本质上更线性,并且能够发生更长的距离。束而不是丝状肌动蛋白能够移动单个细胞。通过与Triton X-100一起孵育,可以从捆包中卸下货物。这些数据表明肌动蛋白捆绑可以提高肌球蛋白运动系统在纳米运输应用中的能力。

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