Chemical Constituents, and their Cytotoxicity, of the Rare Wood Decaying Fungus Xylaria humosa

Sirirath Sodngam; Sasiphimol Sawadsitang; Nuttika Suwannasai; Wiyada Mongkolthanaruk

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Chemical Constituents, and their Cytotoxicity, of the Rare Wood Decaying Fungus Xylaria humosa

机译：稀有木材腐烂真菌Xylaria humosa的化学成分及其细胞毒性

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Samples of Xylaria humosa, a rare species of Xylariaceae, were collected during an investigation into the diversity of the fungus in the Phu Khieo Wildlife Sanctuary, Thailand. Nine compounds were isolated from the species and their structures elucidated by spectroscopic methods. The compounds were ergosterol (1), ergosterol peroxide (2), two meroterpenoids, chevalone B and C (3-4), together with five indole alkaloids, tryptoquivaline L (5), tryptoquivaline M (6), fiscalin A (7), epi-fiscalin A (8) and epi-fiscalin C (9). Compounds 2-9 exhibited variable cytotoxic activity against KB, NCI-H187 and MCF-7 cell lines.

机译：在对泰国Phu Khieo野生动物保护区的真菌多样性进行调查期间，收集了Xylaria humosa（一种Xylariaceae的稀有物种）的样本。从该物种中分离出九种化合物，并通过光谱方法阐明了它们的结构。化合物为麦角固醇（1），过氧化麦角固醇（2），两种甲萜类化合物，白屈烯酮B和C（3-4）以及五种吲哚生物碱，色氨酸喹啉L（5），色氨酸喹啉M（6），紫杉醇A（7）。，表菲西林A（8）和表菲西林C（9）。化合物2-9对KB，NCI-H187和MCF-7细胞系表现出可变的细胞毒活性。

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来源
《Natural product communications》 |2014年第2期|共2页
作者
Sirirath Sodngam; Sasiphimol Sawadsitang; Nuttika Suwannasai; Wiyada Mongkolthanaruk;
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正文语种 eng
中图分类自然科学总论;
关键词
Xylaria humosa; Xylariaceae; Natural products; Cytotoxicity; Tryptoquivaline; Triterpenoid; Quinazolinone.;

机译：湿生木耳;木科;天然产物;细胞毒性;色氨酸;缬氨酸;三萜;喹唑啉酮。;

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1. Chemical Constituents, and their Cytotoxicity, of the Rare Wood Decaying Fungus Xylaria humosa [J] . Sirirath Sodngam, Sasiphimol Sawadsitang, Nuttika Suwannasai, Natural product communications . 2014,第2期

机译：稀有木材腐烂真菌Xylaria humosa的化学成分及其细胞毒性
2. Cytotoxic Metabolites from the Wood-Decayed Fungus Xylaria sp.BCC 9653 [J] . Wipapan PONGCHAROEN, Vatcharin RUKACHAISIRIKUL, Masahiko ISAKA Chemical and Pharmaceutical Bulletin . 2007,第11期

机译：木材腐烂的木霉Xylaria sp.BCC 9653的细胞毒性代谢产物
3. Cytotoxic Constituents from the Vietnamese Fungus Xylaria schweinitzii [J] . Doan Thi Phuong Linh, Bui Thi Thu Hien, Do Duc Que, Natural product communications . 2014,第5期

机译：越南真菌Xylaria schweinitzii的细胞毒性成分
4. The Growth Requirements of a Medicinal Fungus Xylaria nigripes [C] . WAI-JANE HO, CW HSEIH, ZC LIANG, The 7th international medicinal mushroom conference . 2013

机译：药用真菌Xylaria nigripes的生长要求
5. Gene expression profiling of wood decay fungus Fibroporia radiculosa grown on different organic and copper based preservatives [D] . Akgul, Ayfer. 2016

机译：木材腐烂真菌Fibroporia radiculosa在不同有机和铜基防腐剂上的基因表达谱
6. Draft Genome Sequence of the Wood-Decaying Fungus Xylaria sp. BCC 1067 [O] . Sawannee Sutheeworapong, Nuthatai Suteerapongpan, Prasobsook Paenkaew, 2019

机译：木材腐烂真菌Xylaria sp。的基因组序列草案。密件副本1067
7. Cytotoxic Metabolites from the Wood-Decayed Fungus Xylaria sp. BCC 9653 [O] . Wipapan Pongcharoen, Vatcharin Rukachaisirikul, Masahiko Isaka, 2007

机译：来自木腐烂的真菌Xylaria sp的细胞毒性代谢物。 BCC 9653.
8. Cultivation and Spawn Production of the Wood-Decaying Fungus, Shiitake('Lentinula Edodes'): Optimization of Spawn Growth, Production of Degradative Enzymes and Interaction with Wood Inhabitants [R] . Raaska, L. 1993

机译：木瓜腐烂菌（香菇）的栽培和产卵生产：菌种生长的优化，降解酶的产生以及与木材居民的相互作用

Chemical Constituents, and their Cytotoxicity, of the Rare Wood Decaying Fungus Xylaria humosa

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