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首页> 外文期刊>Natural product communications >Biological Studies of Turmeric Oil, Part 3: Anti-Inflammatory and Analgesic Properties of Turmeric Oil and Fish Oil in Comparison with Aspirin
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Biological Studies of Turmeric Oil, Part 3: Anti-Inflammatory and Analgesic Properties of Turmeric Oil and Fish Oil in Comparison with Aspirin

机译:姜黄油的生物学研究,第3部分:姜黄油和鱼油与阿司匹林的比较消炎镇痛特性

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摘要

Turmeric and fish oil have been gaining interest as food supplements because of their beneficial properties. Turmeric oil contains sesquiterpenes and fish oil has eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), possessing anti-inflammatory activity. The present study is to evaluate and compare the anti-inflammatory and analgesic properties of these two natural food products with aspirin as a standard. The percent inhibition as a measure of paw edema for turmeric oil and fish oil at 100 mg/kg was 76% and 31%, respectively, while the percent inhibition by the combination of the two at 100 mg/kg was 62%, which was the same as that of aspirin at the same dose. The inhibitory activity of fish oil at 50 mg/kg was 86% and with an increase in dose the activity decreased. The analgesic activity measured by the tail flick method showed optimum activities for turmeric oil and fish oil at 60 and 90 minutes, respectively, whereas the combination of the two decreased the analgesic activity. Thus the two common food ingredients, oils from turmeric and fish, have desirable biochemical properties to develop further their use as food and medicine.
机译:姜黄和鱼油由于其有益的特性已引起人们对食品补充剂的兴趣。姜黄油中含有倍半萜烯,鱼油中含有二十碳五烯酸(EPA)和二十二碳六烯酸(DHA),具有抗炎活性。本研究旨在评估和比较以阿司匹林为标准的这两种天然食品的抗炎和镇痛作用。姜黄油和鱼油在100 mg / kg时抑制爪水肿的百分率分别为76%和31%,而二者在100 mg / kg的组合下的抑制百分率是62%,为在相同剂量下与阿司匹林相同。鱼油在50 mg / kg时的抑制活性为86%,并且随着剂量的增加,活性降低。用甩尾法测量的镇痛活性分别在60和90分钟时显示出对姜黄油和鱼油的最佳活性,而两者的组合降低了镇痛活性。因此,两种常见的食品成分,姜黄和鱼油,具有理想的生化特性,可以进一步发展其作为食品和药品的用途。

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