A New C-23 Steroid from the Venom of Bufo bufo gargarizans

Luo Shi-Lin; Tian Hai-Yan; Liu Jun-Shan; Wang Ying; Ye Wen-Cai

首页> 外文期刊>Natural product communications >A New C-23 Steroid from the Venom of Bufo bufo gargarizans

【24h】

A New C-23 Steroid from the Venom of Bufo bufo gargarizans

机译：中华蟾蜍毒液中的新型C-23类固醇

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

A new C-23 steroid, (3 beta,5 beta,14 beta)-methyl (3-hydroxy-14,15-epoxy-20-oxo-21-norcholan-24-oate) (1), together with four known ones (2-5), were isolated from the venom of Bufo bufo gargarizans. Their structures were elucidated on the basis of extensive spectroscopic analysis. The cytotoxicity of these compounds was also evaluated against human hepatocarcinoma HepG2 cells. Compound 3 showed significant cytotoxicity with an 1050 value of 16.8 +/- 0.7 mu M.

机译：一种新的C-23类固醇，（3 beta，5 beta，14 beta）-甲基（3-羟基-14,15-环氧20-氧代-21-诺胆聚糖24-酸酯）（1），以及四个已知的那些（2-5）是从中华大蟾蜍的毒液中分离出来的。在广泛的光谱分析的基础上阐明了它们的结构。还评估了这些化合物对人肝癌HepG2细胞的细胞毒性。化合物3显示出明显的细胞毒性，1050值为16.8 +/- 0.7μM.

著录项

来源
《Natural product communications》 |2015年第8期|共2页
作者
Luo Shi-Lin; Tian Hai-Yan; Liu Jun-Shan; Wang Ying; Ye Wen-Cai;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类自然科学总论;
关键词
C-23 steroid; Bufo bufo gargarizans; Cytotoxicities;

机译：C-23类固醇;中华大蟾蜍;细胞毒性;

相似文献

外文文献
中文文献
专利

1. A New C-23 Steroid from the Venom of Bufo bufo gargarizans [J] . Luo Shi-Lin, Tian Hai-Yan, Liu Jun-Shan, Natural product communications . 2015,第8期

机译：中华蟾蜍毒液中的新型C-23类固醇
2. New bufadienolides and C(23) steroids from the venom of Bufo bufo gargarizans. [J] . Tian HY, Wang L, Zhang XQ, Steroids: An International Journal . 2010,第12期

机译：新的bufadienolides和C（23）类固醇从中华大蟾蜍的毒液中提取。
3. Effect of exposure to deltamethrin on the bufadienolide profiles in Bufo bufo gargarizans venom determined by ultra-performance liquid chromatography-triple quadrupole mass spectrometry [J] . Zhou Jing, Zhao Huacong, Chen Luyao, RSC Advances . 2019,第3期

机译：通过超高效液相色谱 - 三重四极谱质谱法测定Bufo Bufo Gargerizans毒液中溴化菊酯对溴化菊酯的影响
4. Toxicity of the Herbicide Butchlor Effects on early period of postembryonic development of Toad Bufo bufo Gargarizans and Bufo naddei Strauch [C] . Bian Shaokang, Chao He, Liang Chuancheng, IT in Medicine and Education (ITME), 2011 International Symposium on . 2011

机译：除草剂丁草胺的毒性对蟾蜍和中华蟾蜍胚后发育早期的影响
5. Bufadienolides in the chemical defenses of the toads, Bufo americanus and Bufo fowleri. [D] . Merovich, Catherine E. 2005

机译：蟾蜍，蟾蜍和蟾蜍的化学防御中的丁二烯内酯。
6. A New Indole Alkaloid from the Toad Venom of Bufo bufo gargarizans [O] . Ying-Hui Dai, Bo Shen, Ming-Yu Xia, 2016

机译：蟾蜍蟾蜍毒液中的一种新的吲哚生物碱
7. A New C23 Steroid from the Venom of Bufo Bufo Gargarizans [O] . Shi-Lin Luo, Hai-Yan Tian, Jun-Shan Liu, 2015

机译：来自Bufo Bufo Gargarizans的毒液的新C23类固醇

A New C-23 Steroid from the Venom of Bufo bufo gargarizans

摘要

著录项

相似文献

相关主题

期刊订阅