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Chemical constituents from the aerial parts of gynura bicolor

机译:双色绞股蓝空中成分的化学成分

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Gynura bicolor (Willd.) DC., is used in folk recipes for the treatment of diabetes mellitus in Jiangsu, Zhejiang and Sichuan province in the south of China. A previous pharmacological study proved that the plant showed significant hypoglycemic activity on normal and alloxan-diabetic mice. In this study, two terpenes, four megastigmane-type norisoprenoids and two glycosides were isolated from the aqueous ethanolic extract of the aerial parts of Gynura bicolor and characterized mainly by NMR spectroscopy and mass spectrometry. These compounds were isolated for the first time from this plant, and no evidence could be found for the previous reported presence of megastigmane-type norisoprenoids in the genus Gynura.
机译:Gynura bicolor(Willd。DC)在中国南方的江苏,浙江和四川被用于民间食谱,以治疗糖尿病。先前的药理研究证明,该植物对正常和四氧嘧啶糖尿病小鼠具有明显的降血糖活性。在这项研究中,从Gynura bicolor地上部分的乙醇提取物中分离出两个萜烯,四个megastigmane型去甲肾上腺素和两个糖苷,并主要通过NMR光谱和质谱进行表征。这些化合物是首次从该植物中分离出来的,没有证据表明以前有报道称雌性菊苣属中存在超大麦胶类型的类异戊二烯类化合物。

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