Mitochondria-Targeted Plastoquinone Derivative SkQ1 Increases Early Reproduction of Drosophila melanogaster at the Cost of Early Survival

E. A. Tsybulko; N. V. Roshina; O. Yu. Rybina

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Mitochondria-Targeted Plastoquinone Derivative SkQ1 Increases Early Reproduction of Drosophila melanogaster at the Cost of Early Survival

机译：线粒体针对的醌醌衍生物SkQ1以早期存活为代价提高了果蝇的早期繁殖。

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It was previously found that 20 pM SkQ1 (10-(6'-plastoquinonyl) decyltriphenylphosphonium) solution increased lifespan of virgin females and males of the fruit fly Drosophila melanogaster with maximal and highly reproducible effect on early survival of females. In this paper we demonstrate that SkQ1 solution of the same concentration does not increase lifespan of mated females and males, early effect on female survival being absent, whereas early fertility and the total number of progeny are elevated in treated flies. Increase in fertility observed in young mated females instead of increase of survival typical for young virgin females might illustrate the trade-off between the fly's lifespan and reproduction.

机译：以前发现20 pM SkQ1（10-（6'-plastoquinonyl）decyltriphenylphosphonium）解决方案增加了初生雌性和果蝇果蝇雄性的寿命，对雌性的早期存活具有最大且高度可重复的作用。在本文中，我们证明了相同浓度的SkQ1溶液不会增加雌雄交配的寿命，不存在对雌性存活的早期影响，而经处理的果蝇的早期生育能力和后代总数增加。在年轻的交配雌性中观察到的生育力增加，而不是年轻的处女雌性典型的存活率增加，可能说明了苍蝇的寿命和繁殖之间的权衡。

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来源
《Biochemistry》 |2010年第3期|共4页
作者
E. A. Tsybulko; N. V. Roshina; O. Yu. Rybina;
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正文语种 eng
中图分类生物化学;
关键词
SkQ1; antioxidant; lifespan; reproduction;

机译：SkQ1;抗氧化剂;寿命;繁殖;

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1. Mitochondria-targeted plastoquinone derivative SkQ1 increases early reproduction of Drosophila melanogaster at the cost of early survival [J] . E A Tsybulko N V Roshina O Yu Rybina E G Pasyukova Biochemistry . 2010,第3期

机译：靶向线粒体的质体醌衍生物SkQ1以早期存活为代价提高了果蝇的早期繁殖
2. The Mitochondria-Targeted Plastoquinone-Derivative SkQ1 Promotes Health and Increases Drosophila melanogaster Longevity in Various Environments [J] . Tsybulko Eugenia, Krementsova Anna, Symonenko Alexander, The journals of gerontology.Series A. Biological sciences and medical sciences . 2017,第4期

机译：线粒体靶向塑性醌衍生物SKQ1促进了健康，并增加了各种环境中的果蝇Melanogaster Longevity
3. Reproducible effects of the mitochondria-targeted plastoquinone derivative SkQ1 on Drosophila melanogaster lifespan under different experimental scenarios [J] . A. V. Krementsova, N. V. Roshina, E. A. Tsybul’ko, Biogerontology . 2012,第6期

机译：在不同的实验情况下，针对线粒体的质体醌衍生物SkQ1对果蝇的寿命具有可重现性
4. Effect of handphone EMF radiation on survival rate and morphological reproductive organ changes of fruit fly (Drosophila melanogaster Meigen, 1830) [C] . Ignatius Sudaryadi, Azizah Nur Rahmawati, Meliana Rizqiyah International Conference on Biological Science . 2020

机译：手机EMF辐射对果蝇生存率和形态生殖器官变化的影响（果蝇Melanogaster Meigen，1830）
5. A cost of reproduction: Oxidative stress susceptibility in Drosophila melanogaster [D] . Wang, Yue 2005

机译：复制的代价：果蝇的氧化应激敏感性
6. The Mitochondria-Targeted Plastoquinone–Derivative SkQ1 Promotes Health and Increases Drosophila melanogaster Longevity in Various Environments [O] . Eugenia Tsybul’ko, Anna Krementsova, Alexander Symonenko, -1

机译：线粒体针对的醌醌衍生物SkQ1在各种环境中促进健康并延长果蝇的寿命。
7. Erratum to: “Effect of Plastoquinone Derivative 10-(6′-Plastoquinonyl)decyltriphenylphosphonium (SkQ1) on Contents of Steroid Hormones and NO Level in Rats” [O] . V. A. Chistyakov, V. A. Serezhenkov, A. A. Alexandrova, 2011

机译：错误至：“塑性醌衍生物10-（6'-塑料醌衍生物10-（6'-塑料醌基）甲基鏻（SKQ1）对类固醇激素含量和大鼠的水平”

Mitochondria-Targeted Plastoquinone Derivative SkQ1 Increases Early Reproduction of Drosophila melanogaster at the Cost of Early Survival

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