Breaking the barrier: membrane fusion triggers innate antiviral immunity

OlagnierD.; HiscottJ.

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Breaking the barrier: membrane fusion triggers innate antiviral immunity

机译：突破障碍：膜融合触发先天性抗病毒免疫

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The sensing of viral infection by the innate immune system is dominated by the recognition of nucleic acids. New data now demonstrate that the fusion of viral and target-cell membranes leads to the activation of an immune response dependent on the adaptor STING.

机译：先天免疫系统对病毒感染的感应主要是通过核酸的识别。现在的新数据表明，病毒膜和靶细胞膜的融合导致依赖于衔接子STING的免疫反应的激活。

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《Nature immunology》 |2012年第8期|共3页
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OlagnierD.; HiscottJ.;
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正文语种 eng
中图分类医学免疫学;
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专利

1. Breaking the barrier: membrane fusion triggers innate antiviral immunity [J] . OlagnierD., HiscottJ. Nature immunology . 2012,第8期

机译：突破障碍：膜融合触发先天性抗病毒免疫
2. Activation of nociceptive fibers following acute skin injury triggers innate antiviral immunity [J] . Handfield C., Kwock J., Hoang P., The Journal of investigative dermatology. . 2018,第5a19期

机译：急性皮肤损伤后伤害纤维的激活触发器先天抗病毒免疫
3. The Alarmin IL-33 Derived from HSV-2-Infected Keratinocytes Triggers Mast Cell-Mediated Antiviral Innate Immunity [J] . Aoki Rui, Kawamura Tatsuyoshi, Goshima Fumi, The Journal of investigative dermatology. . 2016,第6期

机译：源自HSV-2感染的角质形成细胞的Alarmin IL-33触发肥大细胞介导的抗病毒先天免疫
4. Innate immunity triggers IL-32 expression by fibroblast-like synoviooytes in rheumatoid arthritis [C] . Sparsa L., Alsaleh G., Chatelus E., European Congress of Immunology . 2009

机译：先天免疫触发IL-32通过类风湿性关节炎的成纤维细胞样Synoviooys的表达
5. Breaking Down the Barrier: Novel Insights Into the Role of Intestinal Microvilli, M cells, and Exploiting "Innate" B Cells as Therapeutic Targets. [D] . Bennett, Kaila Marie. 2014

机译：打破障碍：肠道微绒毛，M细胞和利用“先天” B细胞作为治疗目标的作用的新颖见解。
6. Lipoteichoic Acid Is Involved in the Ability of the Immunobiotic Strain Lactobacillus plantarum CRL1506 to Modulate the Intestinal Antiviral Innate Immunity Triggered by TLR3 Activation [O] . Hiroya Mizuno, Lorena Arce, Kae Tomotsune, 2020

机译：脂蛋白酸涉及免疫细菌菌株植物乳杆菌CRL1506调节由TLR3激活触发的肠道抗病毒先天免疫的能力。
7. Potential Broad-Spectrum Antiviral Agents Act by Triggering Innate Immunity [O] . David C. Holzman 2016

机译：潜在的广谱抗病毒剂通过触发先天免疫性来作用

Breaking the barrier: membrane fusion triggers innate antiviral immunity

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