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首页> 外文期刊>Nature immunology >The human condition: an immunological perspective.
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The human condition: an immunological perspective.

机译:人类状况:免疫学的观点。

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Despite enormous progress in basic research, there are many gaps in understanding human immunity. Here we describe how new investigational tools and computational methods promise to improve the diagnosis, prognosis and therapy of the many diseases with components from the immune system. In medical school, physicians are taught the four classic signs of inflammation-rubor, dolor, calor and tumor (redness, pain, heat and swelling)-a tetrad first recorded by Celsus in the first century ad . Much progress has been made since then, and these signs can be explained on the basis of the functions of specific cells, molecular mediators and tissue responses. Indeed, the wealth of information about even a simple inflammatory response can be overwhelming when brought together in one place, as in any of the attractive diagrams put out by various journals or drug companies for the edification of clinicians and researchers. But is there really a deep understanding of human immunity?
机译:尽管基础研究取得了巨大进展,但在理解人类免疫力方面仍有许多差距。在这里,我们描述了新的研究工具和计算方法如何有望改善具有免疫系统成分的多种疾病的诊断,预后和治疗。在医学院,医师们学会了炎症的四个经典征兆-毛疹,自发性,热量和肿瘤(发红,疼痛,发热和肿胀),这是Celsus在第一世纪的广告中首次记录的四联征。从那时起已经取得了很大的进步,这些迹象可以根据特定细胞的功能,分子介体和组织反应来解释。的确,将一个简单的炎症反应信息集中到一个地方时,可能会淹没大量信息,就像各种期刊或制药公司为吸引临床医生和研究人员而制作的任何吸引人的图表一样。但是,是否真的对人类免疫力有深刻的了解?

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