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首页> 外文期刊>Nature clinical practice. Oncology >Should young patients with neuroblastoma receive high-dose platinum compounds?
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Should young patients with neuroblastoma receive high-dose platinum compounds?

机译:年轻的神经母细胞瘤患者是否应该接受大剂量的铂化合物?

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摘要

Platinum compounds are the basis for induction and myeloablative strategies in neuroblastoma but can cause ototoxicity. Neuroblastoma typically develops in young children, so this treatment side effect can have important consequences in terms of development. OBJECTIVE To define the extent of ototoxicity caused by high-dose cisplatin (HD-P) induction in previously untreated children with neuroblastoma.
机译:铂化合物是神经母细胞瘤诱导和清髓策略的基础,但会引起耳毒性。神经母细胞瘤通常在幼儿中发展,因此这种治疗副作用会对发育产生重要影响。目的确定以前未经治疗的成神经细胞瘤患儿大剂量顺铂(HD-P)诱导引起的耳毒性程度。

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