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首页> 外文期刊>Nephrology, dialysis, transplantation: official publication of the European Dialysis and Transplant Association - European Renal Association >Adherence to antihypertensive medications: is prescribing the right pill enough?
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Adherence to antihypertensive medications: is prescribing the right pill enough?

机译：坚持使用降压药：开正确的药是否足够？

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摘要

Significant progress has been made in the management of hypertension (HTN) in the last 60 years. A large number of antihypertensive drugs (AHD) is available for effective control of elevated blood pressure (BP) that were also shown to be beneficial in improving all-cause mortality and cardiovascular morbidity in hypertensive individuals. Despite these successes, rates of BP control and outcomes in hypertensive patients remain suboptimal. Therefore, the availability of effective drug therapy itself appears to be insufficient to guarantee desirable results. Adherence to antihypertensive medications is a crucial mediator of favorable outcomes in treating HTN, and non-adherence, in turn, halts BP control. In this review, we will summarize the available evidence on health-related impacts of adherence to AHD, methods for the evaluation of adherence and potential interventions aimed to improve adherence in hypertensive individuals.
机译：在过去的60年中，高血压（HTN）的管理取得了重大进展。大量降压药（AHD）可用于有效控制高血压（BP），也显示出对改善高血压个体的全因死亡率和心血管发病率有益。尽管取得了这些成功，高血压患者的血压控制率和预后仍然不理想。因此，有效药物治疗本身的可用性似乎不足以保证令人满意的结果。坚持使用降压药物是治疗HTN的有利结果的关键介质，不坚持治疗反而会停止BP的控制。在这篇综述中，我们将总结关于坚持AHD对健康相关影响的现有证据，依从性评估方法以及旨在改善高血压个体依从性的潜在干预措施。

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